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United States

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Cat. No.: HY-N18296

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Karelinine

Karelinine is a steroidal alkaloid found in the bulbs of Fritillaria ussuriensis Maxim and Fritillaria karelinii. Karelinine shows accelerated absorption and elimination rates, and increased area under the curve (AUC_0-t) when administered as part of the nanodispersion preparation (FUN) in rat plasma following oral administration.

For research use only. We do not sell to patients.

Formula: C₂₇H₄₁NO₅
Molecular Weight:459.62

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

Karelinine Chemical Structure

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vivo
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

In Vivo

Karelinine (270-2613 mg/kg raw drug equivalent; p.o.; single dose) exhibits the fastest absorption (shortest T_max), highest peak plasma concentration (C_max), largest area under the plasma concentration-time curve (AUC), and shortest elimination half-life (t_1/2) when administered as part of the nanodispersion preparation (FUN) preparation, indicating FUN provides superior absorption efficiency and bioavailability for karelinine in Rattus norvegicus^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

Molecular Weight 459.62
Formula C₂₇H₄₁NO₅
SMILES

C[C@H](CN1)C[C@@]([C@]1([H])[C@H]2C)([H])OC32C[C@H](O)[C@@]4([H])[C@]5([H])CC(C6C[C@H](O)[C@@H](O)C[C@]6(C)[C@@]5([H])CC4=C3C)=O
Structure Classification
- Steroids
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Wu H, et al. Simultaneous Determination and Pharmacokinetics of Three Steroidal Alkaloids in Rat Plasma by UHPLC-MS After Oral Administration of Three Different Preparations of Fritillaria ussuriensis Maxim Bulb. Biomed Chromatogr. 2025;39(3):e6087. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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