1. Natural Products
  2. Plants Steroids
  3. Liliaceae
  4. Fritillaria pallidiflora Schrenk ex Fisch. & C. A. Mey.
  5. Protobioside

Protobioside is a steroidal saponin found in the dry bulbs of Fritillaria pallidiflora Schrenk. Protobioside shows no significant cytotoxic activity against human cancer cells.

For research use only. We do not sell to patients.

Protobioside

Protobioside Chemical Structure

CAS No. : 128052-96-0

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Description

Protobioside is a steroidal saponin found in the dry bulbs of Fritillaria pallidiflora Schrenk. Protobioside shows no significant cytotoxic activity against human cancer cells[1].

In Vitro

Protobioside (3-100 μM; 48 h) shows no in vitro cytotoxic activity against human C6 brain glioma cells and human HeLa cervix cancer cells, with an IC50 value greater than 100 μM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Cytotoxicity Assay[1]

Cell Line: human C6 brain glioma cells, human HeLa cervix cancer cells
Concentration: 3, 6.25, 12.5, 25, 50, 100 μM
Incubation Time: 48 h
Result: Exhibited a cell growth inhibition rate of -5.0 ± 2.9% in human C6 brain glioma cells, with IC50 > 100 μM.
Exhibited a cell growth inhibition rate of 15.3 ± 4.3% in human HeLa cervix cancer cells, with IC50 > 100 μM.
Molecular Weight

903.07

Formula

C45H74O18

CAS No.
SMILES

C[C@@]12[C@]([C@]3([C@](CC1)([C@]4(C)C(=CC3)C[C@@H](O[C@H]5[C@H](O[C@H]6[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O6)[C@@H](O)[C@H](O)[C@@H](CO)O5)CC4)[H])[H])(C[C@]7([C@@]2([C@H](C)[C@](CC[C@H](CO[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)C)(O)O7)[H])[H])[H]

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Product Name:
Protobioside
Cat. No.:
HY-N7920
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