Zhebeirine
Based on 1 Customer Validation
Zhebeirine (Puqiedinone), a steroidal alkaloid, is isolated from the bulbs of Fritillaria puqiensis. Zhebeirine exhibits antitussive and expectorant properties.
For research use only. We do not sell to patients.
- Purity: 99.0%
- CAS No.: 143120-47-2
- Formula: C27H43NO2
- Molecular Weight:413.64
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A549 | CC50 |
29 μM
Compound: 4
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Cytotoxicity against human A549 cells assessed as reduction in cell growth incubated for 48 hrs by CCK8 method
Cytotoxicity against human A549 cells assessed as reduction in cell growth incubated for 48 hrs by CCK8 method
|
[PMID: 38294199] |
| NCI-H460 | CC50 |
49 μM
Compound: 4
|
Cytotoxicity against human NCI-H460 cells assessed as reduction in cell growth incubated for 48 hrs by CCK8 method
Cytotoxicity against human NCI-H460 cells assessed as reduction in cell growth incubated for 48 hrs by CCK8 method
|
[PMID: 38294199] |
Chemical Information
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CAS No. 143120-47-2
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Appearance Solid
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Molecular Weight 413.64
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Formula C27H43NO2
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Color White to off-white
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SMILES
C[C@@]([C@]1([H])C[C@H]2O)(CC2)[C@]3([H])[C@](CC1=O)([H])[C@@](CC[C@@]4([H])[C@@]5([H])CN(C[C@@H]6C)[C@](CC6)([H])[C@@H]4C)([H])[C@@]5([H])C3
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Synonyms
25-Epieduardine; Puqiedinone
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Lin G, et, al. Puqiedinone, a novel 5 alpha-cevanine alkaloid from the bulbs of Fritillaria puqiensis, an antitussive traditional Chinese medicine. J Nat Prod. 1995 Nov; 58(11):1662-7. [Content Brief]
[2]. Jiang Y, et, al. New steroidal alkaloids from the bulbs of Fritillaria puqiensis. Steroids. 2006 Sep; 71(9): 843-8. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)