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Fusarium culmorum

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Bacterial (2) COX (1) Cytochrome P450 (1) Fungal (3) Lipoxygenase (1) Reactive Oxygen Species (ROS) (1)
By Research Areas:	Infection (4)

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Peptides

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Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W392548

1-O-(4-Hydroxybenzoyl)-glycerol	Bacterial Fungal	Infection
1-O-4-Hydroxybenzoyl-glycerol is an antimicrobial agent against Staphylococcus aureus, Escherichia coli, Saccharomyces cerevisiae, and Fusarium culmorum (20 mM, maximum inhibition rate: 70%). 1-O-(4-Hydroxybenzoyl)-glycerol stimulates low skin irritation .

HY-P10329

KK14(R)	Fungal	Infection
KK14(R) is an analog of the de novo synthetic peptide KK14, which exhibits antifungal activity against Fusarium culmorum, Penicillium expansum and Aspergillus niger , with MICs of 6.25, 12.5 and 12.5 μg/mL, respecitvely. KK14(R) exhibits good heat- and pH-stability. KK14(R) exhibits cytotoxicity against cells Caco-2 and RAW264.7 .

HY-W699936

6β-Hydroxy androstenedione	Cytochrome P450	Others
6β-Hydroxy androstenedione is a steroid product that can be isolated from Fusarium culmorum .

HY-183792

Antibacterial agent 347	Bacterial Reactive Oxygen Species (ROS)	Infection
Antibacterial agent 347 (Compound 4d) is an Antibacterial agent. Antibacterial agent 347 exhibits selective antibacterial activity against Streptococcus mutans. Antibacterial agent 347 shows moderate ABTS• ⁺ free radical scavenging activity .

HY-N19724

Buddledin A	Fungal Lipoxygenase COX	Infection
Buddledin A is a 5-LOX inhibitor (IC₅₀ = 50.4 μM) and a COX inhibitor (IC₅₀ = 13.7 μM). Buddedin A inhibits arachidonic acid metabolism via the 5-LOX and COX pathways, suppresses fungal growth, and exerts toxic effects on fish. Buddedin A may play an ecological role in protecting plant roots and stem barks from fungal infection. Buddedin A can be used in studies related to fungal infections .

Cat. No.	Product Name	Target	Research Area

HY-P10329

KK14(R)	Fungal	Infection
KK14(R) is an analog of the de novo synthetic peptide KK14, which exhibits antifungal activity against Fusarium culmorum, Penicillium expansum and Aspergillus niger , with MICs of 6.25, 12.5 and 12.5 μg/mL, respecitvely. KK14(R) exhibits good heat- and pH-stability. KK14(R) exhibits cytotoxicity against cells Caco-2 and RAW264.7 .

1-O-(4-Hydroxybenzoyl)-glycerol	Monophenols Brahea armata S.Watson Phenols Arecaceae Plants Source Classification	Bacterial Fungal
1-O-4-Hydroxybenzoyl-glycerol is an antimicrobial agent against Staphylococcus aureus, Escherichia coli, Saccharomyces cerevisiae, and Fusarium culmorum (20 mM, maximum inhibition rate: 70%). 1-O-(4-Hydroxybenzoyl)-glycerol stimulates low skin irritation .

6β-Hydroxy androstenedione	Microorganisms Cardiacglycosides Steroids Source Classification	Cytochrome P450
6β-Hydroxy androstenedione is a steroid product that can be isolated from Fusarium culmorum .

Buddledin A	Structural Classification Terpenoids Sesquiterpenes Scrophulariaceae Plants Buddleja davidi Franch. Source Classification	Fungal Lipoxygenase COX
Buddledin A is a 5-LOX inhibitor (IC₅₀ = 50.4 μM) and a COX inhibitor (IC₅₀ = 13.7 μM). Buddedin A inhibits arachidonic acid metabolism via the 5-LOX and COX pathways, suppresses fungal growth, and exerts toxic effects on fish. Buddedin A may play an ecological role in protecting plant roots and stem barks from fungal infection. Buddedin A can be used in studies related to fungal infections .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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Fusarium culmorum

Inhibitors & Agonists

Peptides

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Natural
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