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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
GES1
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "GES1" in MCE Product Catalog:
Cat. No.: HY-N7161
CAS No.: 466663-11-6
Target:
Cat. No.: HY-170937
CAS No.: 2998940-98-8
Research Areas:
Urease-IN-20 (compound XBP2) is an inhibitor of Helicobacter pylori (H. pylori). Urease-IN-20 inhibits H. pylori with an IC50 of 0.14 μM. Urease-IN-20 reduces cell Apoptosis and decreases ROS and γH2AX in GES-1 cells infected with H. pylori. Urease-IN-20 exhibits significant gastric mucosal protective effects. Urease-IN-20 shows the potential for H. pylori research [1].
Cat. No.: HY-175779
Target:
Research Areas:
TDP1-IN-4 (Compound 33) is a Tyrosyl-DNA phosphodiesterase 1 (TDP1) inhibitor with an IC50 of 0.90 μM. TDP1-IN-4 has a strong synergistic effect with Camptothecin (HY-16560) in SK-Mel-2 cells, but not in cancer cells (A549, HCT-116 and MCF-7 cells) and non-cancerous Ges-1 cells. TDP1-IN-4 can be used for cancer chemotherapy and radiotherapy research [1].
Cat. No.: HY-116578R
CAS No.: 14008-44-7
Synonyms: EXP999 (Standard); RP9965 (Standard)
Target:
Research Areas:
Metopimazine (Standard) is the analytical standard of Metopimazine. This product is intended for research and analytical applications. Metopimazine (EXP999) is a phenothiazine derivative used to prevent emesis during chemotherapy. Metopimazine belongs to the anti-dopaminergic anti-emetics (ADA) class. Metopimazine can be used for the research of gastroenteritis (GE) .
Cat. No.: HY-146384
CAS No.: 2986647-41-8
Target:
Research Areas:
CRM1 degrader 1 is a CRM1 degrader. CRM1 degrader 1 induces mitochondrial pathway-mediated apoptosis. CRM1 degrader 1 dose-dependently reduces CRM1 protein levels via the ubiquitin-proteasome pathway, promotes nuclear accumulation of p53, and regulates Bcl-2 family proteins and caspase activation. CRM1 degrader 1 is applicable to gastric cancer-related research [1].
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
