5 Results for "

Guanfu base A

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "Guanfu base A" in MCE Product Catalog:

Cat. No.: HY-N1483
CAS No.: 1394-48-5
Guanfu base A is an antiarrhythmic alkaloid isolated from Aconitum coreanum and is a potent noncompetitive CYP2D6 inhibitor, with a Ki of 1.20 μM in human liver microsomes (HLMs) and a Ki of 0.37 μM for the human recombinant form (rCYP2D6). Guanfu base A is also a potent competitive inhibitor of CYP2D in monkey (Ki of 0.38 μM) and dog (Ki of 2.4 μM) microsomes . Guanfu base A also inhibits HERG channel current .
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Cat. No.: HY-N5005
CAS No.: 4758-99-0
Synonyms: Atisinium chloride
Guanfu base H (Atisinium chloride) is a diterpenoid alkaloid isolated from Aconitum coreanum and has antiplasmodial activity against the malarial Plasmodium falciparum strains TM4/8.2 (wild type) and K1CB1 with IC50 values of 4 μM and 3.6 μM, respectively .
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Cat. No.: HY-N5006
CAS No.: 78969-72-9
Guanfu base G is an antiarrhythmic alkaloid isolated from Aconitum coreanum. Guanfu base G inhibits HERG channel current with an IC50 of 17.9 μM .
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Cat. No.: HY-N1483A
CAS No.: 618094-85-2
Guanfu base A hydrochloride is an antiarrhythmic alkaloid with the ability to inhibit CYP2D6 enzyme activity. Guanfu base A hydrochloride can be used to inhibit arrhythmia-related diseases. Guanfu base A hydrochloride exhibits inhibitory effects on CYP2D6 in different species of organisms, including humans, monkeys, and dogs. The biological activity of Guanfu base A hydrochloride makes it have potential clinical application value .
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Cat. No.: HY-N17965
CAS No.: 103847-13-8
Guan-fu base Z (Compound 9) is a diterpenoid alkaloid that can be isolated from the whole herb of Aconitum tanguticum var. trichocarpum .
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