1 Result for "

H-Trp-Tyr-OH

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "H-Trp-Tyr-OH" in MCE Product Catalog:

H-Trp-Tyr-OH
H-Trp-Tyr-OH
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Cat. No.: HY-P4610
CAS No.: 19653-76-0
Target:  

GLP Receptor

Research Areas:  

Metabolic Disease

H-Trp-Tyr-OH is an orally active tryptophan-tyrosine dipeptide with blood-brain barrier permeability. H-Trp-Tyr-OH exerts physiological regulatory effects by stimulating enteroendocrine cells to secrete glucagon-like peptide GLP-1. In mouse models of tauopathies, H-Trp-Tyr-OH inhibits tau phosphorylation, reduces the level of neurofibrillary tangles, increases dopamine turnover, upregulates synapsin expression, and elevates cecal short-chain fatty acid levels, thereby improving behavioral deficits and extending lifespan. H-Trp-Tyr-OH can be used in research related to impaired glucose tolerance and tauopathies .
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