2 Results for "

HS-5 cells

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "HS-5 cells" in MCE Product Catalog:

1
Dichotomitin
Dichotomitin
0 Images
1 Cited Publications
Cat. No.: HY-N2120
CAS No.: 88509-91-5
Category:  

Iridaceae Flavonoids Other Diseases Phenols Polyphenols Plants Belamcanda chinensis (Linn.) Redouté Disease Research Fields Isoflavones

Target:  

Reactive Oxygen Species (ROS) SOD RUNX

Dichotomitin is an isoflavonoid compound isolated from the rhizomes of Belamcanda chinensis. Dichotomitin exhibits antioxidant activity, alleviates oxidative stress, reduces intracellular reactive oxygen species (ROS) levels, and upregulates the expression of SOD1, SOD2 and CAT. Dichotomitin increases ALP activity while upregulating the expression of RUNX2, OPN and OCN. Dichotomitin has antitussive activity and helps improve symptoms of upper respiratory tract infections .
loading...
    loading...
View All Sizes
MA191
MA191
0 Images
Cat. No.: HY-175273
Target:  

PROTACs FLT3 HSP STAT Apoptosis Caspase ERK Akt

Research Areas:  

Cancer

MA191 is a FLT3 PROTAC degrader. MA191 targets and degrades mutant FLT3-ITD protein by recruiting the VHL E3 ligase in a manner dependent on ubiquitination and BIM, thereby blocking aberrant downstream MAPK/STAT5 signaling pathways and inducing apoptosis. MA191 can be used in research related to acute myeloid leukemia .
loading...
    loading...
View All Sizes
Assay Types