88509-91-5
Chemical Structure
Dichotomitin
- CAS No.: 88509-91-5
- Formula:C18H14O8
- Molecular Weight:358.30
IUPAC Name: 9-hydroxy-7-(3-hydroxy-4,5-dimethoxyphenyl)-8H-[1,3]dioxolo[4,5-g]chromen-8-one
InChIKey: PFFOGGCBLWTCPM-UHFFFAOYSA-N
SMILES: O=C1C(C2=CC(OC)=C(OC)C(O)=C2)=COC3=CC(OCO4)=C4C(O)=C13
Biological Activity: Dichotomitin is an isoflavonoid compound isolated from the rhizomes of Belamcanda chinensis. Dichotomitin exhibits antioxidant activity, alleviates oxidative stress, reduces intracellular reactive oxygen species (ROS) levels, and upregulates the expression of SOD1, SOD2 and CAT. Dichotomitin increases ALP activity while upregulating the expression of RUNX2, OPN and OCN. Dichotomitin has antitussive activity and helps improve symptoms of upper respiratory tract infections[1][2][3][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Dichotomitin | 99.18% | Dichotomitin is an isoflavonoid compound isolated from the rhizomes of Belamcanda chinensis. Dichotomitin exhibits antioxidant activity, alleviates oxidative stress, reduces intracellular reactive oxygen species (ROS) levels, and upregulates the expression of SOD1, SOD2 and CAT. Dichotomitin increases ALP activity while upregulating the expression of RUNX2, OPN and OCN. Dichotomitin has antitussive activity and helps improve symptoms of upper respiratory tract infections. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Han M, et al. Dichotomitin promotes osteoblast differentiation and improves osteoporosis by inhibiting oxidative stress. Journal of orthopaedic surgery and research. 2025 Jan 03;20(1):6. [Content Brief]
- [2]. Zhang KX, et al. Characterization of the metabolites of dichotomitin in rat, monkey and human by ultra-high-performance liquid chromatography/high-resolution mass spectrometry. Rapid communications in mass spectrometry : RCM. 2021 Dec 15;35(21):e9182.
- [3]. Xie GY, et al. Phenolic metabolite profiles and antioxidants assay of three Iridaceae medicinal plants for traditional Chinese medicine "She-gan" by on-line HPLC-DAD coupled with chemiluminescence (CL) and ESI-Q-TOF-MS/MS. Journal of pharmaceutical and biomedical analysis. 2014 Sep;98:40-51. [Content Brief]
- [4]. Mo, X, et al. Chemical composition profiles of Apis cerana fabr. produced Acacia honey: a comparative study on optimal non-acidified ACN extraction with water-dilution by widely targeted metabolomics. Eur Food Res Technol 251, 2699–2717 (2025).
