4 Results for "

Heat Shock Protein Inhibitor I

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "Heat Shock Protein Inhibitor I" in MCE Product Catalog:

7
7 Cited Publications
Cat. No.: HY-100110
CAS No.: 218924-25-5
Purity:  99.04%
Synonyms: Heat Shock Protein Inhibitor I
Target:  

HSP

Research Areas:  

Cancer

KNK437 is a HSP inhibitor, and inhibits the induction of HSP105, HSP70, and HSP40.
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Cat. No.: HY-N12887
CAS No.: 114582-75-1
Mycothiazole is an inhibitor for mitochondrial electron transport chain (ETC) complex I. Mycothiazole exhibits cytotoxicity in cancer cells Huh7 (IC50 is 55.8 μM), U87 and MCF7. Mycothiazole induces apoptosis in Huh7. Mycothiazole utilizes the unfolded protein response (UPR) and heat shock response (HSR) pathway involved transcription factors ATFS-1 and HSF1, to extend the lifespan of C. elegans .
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Cat. No.: HY-100110R
CAS No.: 218924-25-5
Synonyms: Heat Shock Protein Inhibitor I (Standard)
Target:  

HSP Reference Standards

Research Areas:  

Cancer

KNK437 (Standard) is the analytical standard of KNK437 (HY-100110). This product is intended for research and analytical applications. KNK437 is a HSP inhibitor, and inhibits the induction of HSP105, HSP70, and HSP40.
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Cat. No.: HY-117252
CAS No.: 1118861-60-1
Research Areas:  

Infection Cancer

HS-72 is a selective allosteric inducible heat shock protein 70 Hsp70i inhibitor. HS-72 reduces ATP affinity of Hsp70i, elevates caspase 3/7 apoptotic activity, and promotes degradation of Hsp70 client proteins, including HER2 and Akt, and blocks DENV entry by disrupting Hsp70i association with the DENV receptor complex. HS-72 can be used for breast cancer and dengue virus infection research .
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