23 Results for "

Hyaluronidase

" in MedChemExpress (MCE) Product Catalog:
Products (23)

23 Results for "Hyaluronidase" in MCE Product Catalog:

19
19 Publications Verification
Cat. No.: HY-107910
CAS No.: 37326-33-3
Synonyms: Hyaluronate 4-glycanohydrolase, Bovine testes; Hyaluronoglucosaminidase, Bovine testes
Target:  

NF-κB

Research Areas:  

Inflammation/Immunology Cancer

Hyaluronidase, Bovine testes (Hyaluronate 4-glycanohydrolase; Hyaluronoglucosaminidase) is an endoglycosidase that depolymerizes Hyaluronic acid (HA) (HY-B0633A) by cleavage of glycosidic bonds. Hyaluronidase degrades HA and activates membrane receptors that trigger pathways converging in NF-κB activation. Hyaluronidase is employed in the research of granulomatous foreign body reactions, soft-tissue necrosis caused by vascular compromise and uncomplicated nodules, overcorrection, inflamed nodules or tissue ischemia associated with HA filler injection .
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19
19 Publications Verification
Cat. No.: HY-108903
CAS No.: 37326-33-3
Synonyms: VorHyaluronidase alfa; rHuPH 20
Research Areas:  

Metabolic Disease

Hyaluronidase (human recombinant) (Vorhyaluronidase alfa; rHuPH 20) is an enzyme that catalyzes the degradation of hyaluronic acid. Hyaluronidase (human recombinant) is used to improve the absorption and dispersal of parenteral fluids, medications, and contrast media .
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15
15 Cited Publications
Cat. No.: HY-108903A
CAS No.: 37326-33-3
Purity:  95.00%
Research Areas:  

Endocrinology

Hyaluronidase, Ovine testes is an endoglycosidase. Hyaluronidase, Ovine testes specifically degrades Hyaluronic acid (HY-B0633A) and Chondroitin sulfate (HY-B2162) by hydrolyzing β-glycosidic bonds in acidic mucopolysaccharides. Hyaluronidase, Ovine testes disperses follicular cells during fertilization by breaking down the hyaluronic acid-rich cumulus. Hyaluronidase, Ovine testes can be used in the study of fertility-related diseases .
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1
1 Cited Publications
Cat. No.: HY-P70411
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rHuHyaluronidase-1/HYAL1, His; Hyaluronidase-1; Hyal-1; Hyaluronoglucosaminidase-1; Lung Carcinoma Protein 1; LuCa-1; HYAL1; LUCA1
Species:  
Source:  
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Cat. No.: HY-N0616
CAS No.: 6807-83-6
Trifolirhizin is a pterocarpan flavonoid found in the roots of Sophora flavescens. Trifolirhizin is a tyrosinase inhibitor with an IC50 value of 506.77 μM. Trifolirhizin reduces intracellular melanin production and modulates multiple signaling pathways including NFκB-MAPK, AMPK/mTOR, PI3K/Akt, MAPK-NFATc1 and EGFR-MAPK. Trifolirhizin targets biological molecules including PTK6 and COX-2, inhibits the activities of hyaluronidase, collagenase and elastase, induces apoptosis, autophagy and cell cycle arrest, and suppresses the proliferation, migration and invasion of cancer cells. Trifolirhizin exerts diverse pharmacological effects including anti-inflammatory, anti-asthmatic, bone-protective, renoprotective, antibacterial, antifungal, hepatoprotective, antiplatelet, estrogenic and wound-healing activities. Trifolirhizin can be used to investigate a broad range of malignant, inflammatory, metabolic and infectious disorders .
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Cat. No.: HY-P991212
CAS No.: 2636716-20-4
Synonyms: ALT-B4

Target:  

Glycosidase

Research Areas:  

Cancer

Berahyaluronidase alfa (ALT-B4) is a recombinant hyaluronidase engineered from human hyaluronidase PH20. Berahyaluronidase alfa features favorable structural stability and enzymatic activity, and can be used to enhance drug absorption and dispersion in subcutaneous or intradermal administration .
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Cat. No.: HY-N2589
CAS No.: 19416-87-6
Isosaponarin is a flavone glycoside isolated from wasabi leaves. Isosaponarin is a P4HA2 enzymatic agonist. Isosaponarin increases collagen synthesis via up-regulated TGF-β type II receptor (TβR-II) and prolyl 4-hydroxylase (P4H) proteins production, promoting skin health and wound healing. Isosaponarin-rich plants exhibit strong antimicrobial, antioxidant, anti-hyaluronidase, antiplatelet, anti-atopic dermatitis, and anti-tumor effects .
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Cat. No.: HY-124504
CAS No.: 23255-59-6
Lunularic acid is a dihydrostilbene compound with anti-hyaluronidase activity (IC50: 0.13 nM). Lunularic acid can be used as an endogenous growth inhibitor in liverworts, replacing the function of abscisic acid in higher plants .
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Cat. No.: HY-W540661
CAS No.: 57282-61-8
Hyaluronic acid tetrasaccharide, 98% is a naturally occurring polysaccharide found in the extracellular matrix of connective tissues. Hyaluronic acid tetrasaccharide can be used as a substrate for enzyme assays to characterize hyaluronidases and other hyaluronic acid-degrading enzymes.
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Cat. No.: HY-N15572
CAS No.: 84297-49-4
1,2,4,6-Tetra-O-galloyl-β-D-glucose is an antioxidant found in Eucalyptus globulus. 1,2,4,6-Tetra-O-galloyl-β-D-glucose has significant superoxide dismutase (SOD)-like antioxidant activity (EC50: 1.55 μM). 1,2,4,6-Tetra-O-galloyl-β-D-glucose can inhibit tyrosinase (IC50: 0.59 mM) and hyaluronidase (IC50: 0.68 mM). 1,2,4,6-Tetra-O-galloyl-β-D-glucose can be used in food antioxidants, cosmetics anti-melanogenesis and anti-allergy/anti-inflammatory research .
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Cat. No.: HY-138050
CAS No.: 96895-25-9
Synonyms: (-)-Nyasol; (Z)-Hinokiresinol; cis-Hinokiresinol
Nyasol ((-)-Nyasol) is an active compound that has antifungal, antibacterial, antileishmanial, hyaluronidase inhibition activities. Nyasol inhibits LTB4 binding to human neutrophils. Nyasol suppresses neuroinflammatory response through the inhibition of I-κB degradation in LPS (HY-D1056)-stimulated BV-2 microglial cells .
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Cat. No.: HY-N16652
CAS No.: 168010-10-4
Foeniculoside I is a stilbene trimer glycoside compound found in Foeniculum vulgare. Foeniculoside I has strong antioxidant activity and moderate hyaluronidase inhibitory activity. Foeniculoside I can be used for the researches of cancer, inflammation and immunology .
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Cat. No.: HY-E70182
Synonyms: EC:3.2.1.35; HYAL2
Hyaluronidase 2 (EC:3.2.1.35; HYAL2) is a hyaluronidase. Hyaluronidase 2 cleaves high-molecular-weight hyaluronan into intermediate, ~20 kDa, and tetrasaccharide fragments. Hyaluronidase 2 directly interacts with CD44 and ERM proteins, reduces CD44 hyaluronan binding capacity and ERM activation. Hyaluronidase 2 can be used for the research of gliomas, inflammatory bowel disease, congenital heart defects, heart failure .
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Cat. No.: HY-107940
CAS No.: 12211-28-8
Target:  

Proteolytic Enzyme

Research Areas:  

Others

Sutilains is a proteolytic enzyme that dissolves necrotic tissue and hyaluronidase. Sutilains can be used as a topical debriding agent in burns .
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Cat. No.: HY-P992147
CAS No.: 3057275-55-2

Target:  

Inhibitory Antibodies

Research Areas:  

Others

Zinihyaluronidase alfa is a hyaluronidase .
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Cat. No.: HY-108903B
Target:  

Glycosidase

Research Areas:  

Metabolic Disease

Hyaluronidase, Streptomyces hyalurolyticus (EC 3.2.1.35) degrades hyaluronan and has been found to be inappropriately regulated during cancer progression. Hyaluronidase randomly cleaves β-N-acetylhexosamine-[1→4] glycosidic bonds in hyaluronic acid, chondroitin, and chondroitin sulfates.
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Cat. No.: HY-P79168
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Hyaluronidase; SAG1197
Species:  
Source:  
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Cat. No.: HY-N20687
CAS No.: 1235289-00-5
Shimobashiraside D is a dihydrochalcone C-glycoside found in the aerial parts of Keiskea japonica and is inactive against hyaluronidase .
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Cat. No.: HY-P79066
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Hyaluronidase 2; LUCA2; LuCa-2; Hyaluronoglucosaminidase 2; Lung Carcinoma Protein 2; Lysosomal Hyaluronidase; Hyaluronoglucosaminidase-2
Species:  
Source:  
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Cat. No.: HY-P703763
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Hyaluronidase-2; Hyaluronoglucosaminidase-2; Hyal2; Hyal-2
Species:  
Source:  
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