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Hyaluronidase, Streptomyces hyalurolyticus

19 Cited Publications
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Based on 19 publication(s) in Google Scholar

Hyaluronidase, Streptomyces hyalurolyticus (EC 3.2.1.35) degrades hyaluronan and has been found to be inappropriately regulated during cancer progression. Hyaluronidase randomly cleaves β-N-acetylhexosamine-[1→4] glycosidic bonds in hyaluronic acid, chondroitin, and chondroitin sulfates.

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  • Hyaluronidase, Streptomyces hyalurolyticus Chemical Structure
    Hyaluronidase, Streptomyces hyalurolyticus Chemical Structure
  • Experimental Validation Results for Hyaluronidase, Streptomyces hyalurolyticus
  • Experimental Validation Results for Hyaluronidase, Streptomyces hyalurolyticus
  • Experimental Validation Results for Hyaluronidase, Streptomyces hyalurolyticus
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IHCIn Vivo Efficacy Study
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  • Hyaluronidase, Streptomyces hyalurolyticus Chemical Structure
    Hyaluronidase, Streptomyces hyalurolyticus Chemical Structure
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    Hyaluronidase, Streptomyces hyalurolyticus purchased from MedChemExpress. Usage Cited in: Cancer Res. 2025 Aug 1;85(15):2805-2819. [Abstract]

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     B, Growth curves of PDX mice treated with PBS, everolimus, PEGPH20 (Hyaluronidase), and everolimus combined with PEGPH20 (n = 5 per group). C, H&E staining and IHC were used to demonstrate the effects of different drug administration strategies on tumor stroma and CD31+ cell and αSMA+ cell number

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    Hyaluronidase, Streptomyces hyalurolyticus purchased from MedChemExpress. Usage Cited in: Cancer Res. 2025 Aug 1;85(15):2805-2819. [Abstract]

    Customer Validation
     E and F, Flow cytometry analysis was used to demonstrate the effects of different drug administration strategies on the proportion of TipECs. Hyaluronidase (PEGPH20)

  • 1/16

    Hyaluronidase, Streptomyces hyalurolyticus purchased from MedChemExpress. Usage Cited in: Cancer Res. 2025 Aug 1;85(15):2805-2819. [Abstract]

    Customer Validation
     The effects of different drug administration strategies in the BON1+ HUVEC (4:1) model. Hyaluronidase (PEGPH20)

  • Hyaluronidase, Streptomyces hyalurolyticus