1 Result for "

JNK3 inhibitor-9

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "JNK3 inhibitor-9" in MCE Product Catalog:

Cat. No.: HY-168859
Target:  

JNK GSK-3 Amyloid-β

Research Areas:  

Neurological Disease

JNK3 inhibitor-9 (Compound 24a) is a potent, selective and BBB-permeable JNK3 inhibitor with an IC50 value of 12 nM. JNK3 inhibitor-9 also potently inhibits GSK3α/β (IC50s: 14 and 35 nM, respectively) involved in Tau phosphorylation. JNK3 inhibitor-9 reduces c-Jun and APP phosphorylation. JNK3 inhibitor-9 protects neurons from 1-42 toxicity .
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