1 Result for "

KZL-064

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "KZL-064" in MCE Product Catalog:

Cat. No.: HY-189233
CAS No.: 2773345-67-6
Target:  

HDAC Apoptosis

Domaines de recherche:  

Cancer

KZL-064 is an orally active HDAC1 ligand that directly binds to HDAC1. KZL-064 inhibits the proliferation, migration, and invasion of hepatocellular carcinoma cells, and induces apoptosis and G2/M phase cell cycle arrest. The antiproliferative, proapoptotic, and cell cycle regulatory effects of KZL-064 are partially dependent on HDAC1, while its inhibitory effects on migration and invasion also involve HDAC1-independent mechanisms. KZL-064 is applicable to hepatocellular carcinoma research .
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