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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
15 Results for "
Kininogen
" in MedChemExpress (MCE) Product Catalog:
Products (15)
15 Results for "Kininogen" in MCE Product Catalog:
1
1 Cited Publications
Synonyms: Lumi-Phos Plus; Lumigen PPD; PPD
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Bromelain is an anti-inflammatory agent derived from pineapple stem that acts through down-regulation of plasma kininogen, inhibition of Prostaglandin E2 expression, degradation of advanced glycation end product receptors and regulation of angiogenic biomarkers as well as antioxidant action upstream in the COX-pathway . Bromelain exhibits various fibrinolytic, antiedematous, antithrombotic, and anti-inflammatory activities. Bromelain also possesses some anticancerous activities and promotes apoptotic cell death .
Cat. No.: HY-122542
CAS No.: 71142-71-7
Domaines de recherche:
PPACK is a potent, peptidic inhibitor targeting thrombin and granzyme GZMK. PPACK specifically blocks the activities of thrombin and GZMK, thereby inhibiting thrombin-mediated PAR-1 cleavage, as well as downstream inflammatory and procoagulant signaling pathways. Through stabilizing IκB proteins, blocking NF-κB activation and reducing systemic levels of proinflammatory/procoagulant biomarkers, PPACK exerts multiple effects including anti-inflammatory, antithrombotic, barrier repair, and inhibition of atherosclerotic plaque progression. PPACK binds to platelets without interference from kininogen, effectively limiting acute thrombus growth and reducing eosinophil infiltration and goblet cell hyperplasia in asthma models. PPACK is an important tool molecule for investigating the mechanisms of atherosclerosis, asthma and related thromboinflammatory diseases .
Cat. No.: HY-P99110
CAS No.: 1426055-14-2
Synonyms: SHP643; DX-2930; X124-G01
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Cat. No.: HY-103293A
Pureté: 99.44%
Synonyms: Kallidin (380-389) (human, porcine, bovine) TFA
Target:
Domaines de recherche:
Cardiovascular Disease Neurological Disease Inflammation/Immunology
Cat. No.: HY-E70389A
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Domaines de recherche:
Kallikrein, Cynomolgus Monkey is proteolytically cleaves high molecular weight kininogen to generate the potent vasodilator and the pro-inflammatory peptide, bradykinin. can be used for the research of inflammation .
Cat. No.: HY-126609
CAS No.: 38957-41-4
Synonyms: Pentoil; Nandron
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Emorfazone (Pentoil) is a non-steroidal anti-inflammatory drug with oral activity. Emorfazone can significantly inhibit the release of bradykinin-like substances and kininogen. Emorfazone has anti-inflammatory and analgesic activity .
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Domaines de recherche:
Cardiovascular Disease Neurological Disease Inflammation/Immunology
Cat. No.: HY-RS24100
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Kng1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Kng1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-103293B
CAS No.: 84640-50-6
Synonyms: Kallidin (380-389) (human, porcine, bovine) tetraacetate
Target:
Domaines de recherche:
Cardiovascular Disease Neurological Disease Inflammation/Immunology
Cat. No.: HY-108292R
CAS No.: 66532-86-3
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Domaines de recherche:
Propacetamol (hydrochloride) (Standard) is the analytical standard of Propacetamol (hydrochloride). This product is intended for research and analytical applications. Propacetamol hydrochloride is a potent, peptidic inhibitor targeting thrombin and granzyme GZMK. Propacetamol hydrochloride specifically blocks the activities of thrombin and GZMK, thereby inhibiting thrombin-mediated PAR-1 cleavage, as well as downstream inflammatory and procoagulant signaling pathways. Through stabilizing IκB proteins, blocking NF-κB activation and reducing systemic levels of proinflammatory/procoagulant biomarkers, Propacetamol hydrochloride exerts multiple effects including anti-inflammatory, antithrombotic, barrier repair, and inhibition of atherosclerotic plaque progression. Propacetamol hydrochloride binds to platelets without interference from kininogen, effectively limiting acute thrombus growth and reducing eosinophil infiltration and goblet cell hyperplasia in asthma models. Propacetamol hydrochloride is an important tool molecule for investigating the mechanisms of atherosclerosis, asthma and related thromboinflammatory diseases .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
