1 Result for "

LY-314228

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "LY-314228" in MCE Product Catalog:

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Cat. No.: HY-117792
CAS No.: 182633-54-1
Target:  

5-HT Receptor

Research Areas:  

Inflammation/Immunology

LY314228 is an aminoguanidine 5-HT2 antagonist with relative selectivity for 5-HT2A receptors (IC50: 147.9 nM). The Ki values of LY314228 targeting different 5-HT subtypes are 65 nM (5-HT 2A), 1214 nM (5-HT 2B), and 168 nM (5-HT 2C), respectively. LY314228 is an effective inhibitor of 5-HT-induced paw edema in rats with an ED50 of 6.4 mg/kg in ovariectomized female rats. .
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