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MAO-B-IN-54

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-131660

    Monoamine Oxidase Amyloid-β Reactive Oxygen Species (ROS) Neurological Disease
    MAO-B-IN-54 is a selective, reversible and competitiv monoamine oxidase B (MAOB) inhibitor with a human IC50 of 0.052 μM and a Ki of 0.028 μM. MAO-B-IN-54 shows weak activity MAOA. MAO-B-IN-54 occupies both the entrance and substrate cavity of MAOB, forming hydrophobic and hydrogen bonding interactions. MAO-B-IN-54 inhibits aggregation and ROS production. MAO-B-IN-54 can be used for the research of Alzheimer’s disease .
    MAO-B-IN-54

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