1 Result for "

MDCK-hMDR1 cells

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "MDCK-hMDR1 cells" in MCE Product Catalog:

Cat. No.: HY-187998
CAS No.: 3034975-33-9
Target:  

Ras PERK

Research Areas:  

Cancer

AM-8719 is an orally active, blood-brain barrier-penetrant KRAS G12C inhibitor. AM-8719 binds covalently to KRAS G12C, inhibits SOS1-catalyzed GDP/GTP exchange, and suppresses downstream ERK phosphorylation. AM-8719 exhibits antiproliferative activity against KRAS G12C tumor cells. AM-8719 can be used for the research of KRAS G12C-positive cancers .
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