2 Results for "

Manninotriose

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Manninotriose" in MCE Product Catalog:

1
Manninotriose
Manninotriose
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Cat. No.: HY-N0913
CAS No.: 13382-86-0
Category:  

other families Polysaccharides Other Diseases Plants Disease Research Fields Saccharides

Target:  

Thymidylate Synthase Antifolate

Manninotriose is a natural functional trisaccharide composed of three mannose molecules. Manninotriose binds to dihydrofolate reductase via hydrogen bond formation with Arg28. Manninotriose binds to thymidylate synthase via hydrogen bond formation with Arg50. Manninotriose acts as a membrane protectant and helps improve stress tolerance. Manninotriose can be used in research related to acute lymphoblastic leukemia .
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Manninotriose (Standard)
Manninotriose (Standard)
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Cat. No.: HY-N0913R
CAS No.: 13382-86-0
Category:  

other families Polysaccharides Microorganisms Plants Saccharides

Target:  

Reference Standards Antifolate Thymidylate Synthase

Wy-45494 (hydrochloride) (Standard) is the analytical standard of Wy-45494 (hydrochloride). This product is intended for research and analytical applications. Wy-45494 hydrochloride (N-Desmethyl Venlafaxine hydrochloride; Wy 45494) is a minor active metabolite of the selective norepinephrine and serotonin reuptake inhibitor (SNRI) venlafaxine. It is formed from venlafaxine via the cytochrome P450 (CYP) isomer CYP3A4.2. Wy-45494 hydrochloride inhibits norepinephrine and serotonin reuptake in rat synaptosomal preparations (IC50s of 4.7 and 1.6 μM, respectively). In vivo, Wy-45494 hydrochloride reversed reserpine-induced hypothermia in mice at a minimum effective dose (MED) of 10 mg/kg.
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