Manninotriose (Standard)
Wy-45494 (hydrochloride) (Standard) is the analytical standard of Wy-45494 (hydrochloride). This product is intended for research and analytical applications. Wy-45494 hydrochloride (N-Desmethyl Venlafaxine hydrochloride; Wy 45494) is a minor active metabolite of the selective norepinephrine and serotonin reuptake inhibitor (SNRI) venlafaxine. It is formed from venlafaxine via the cytochrome P450 (CYP) isomer CYP3A4.2. Wy-45494 hydrochloride inhibits norepinephrine and serotonin reuptake in rat synaptosomal preparations (IC50s of 4.7 and 1.6 μM, respectively). In vivo, Wy-45494 hydrochloride reversed reserpine-induced hypothermia in mice at a minimum effective dose (MED) of 10 mg/kg.
For research use only. We do not sell to patients.
- CAS No.: 13382-86-0
- Formula: C18H32O16
- Molecular Weight:504.44
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 13382-86-0
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Molecular Weight 504.44
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Formula C18H32O16
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SMILES
O[C@@H]([C@@H](O)[C@H](O)[C@@H](O)C=O)CO[C@H]([C@@H]([C@@H](O)[C@H]1O)O)O[C@@H]1CO[C@H]([C@@H]([C@@H](O)[C@H]2O)O)O[C@@H]2CO
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. dos Santos R, et al. Manninotriose is a major carbohydrate in red deadnettle (Lamium purpureum, Lamiaceae). Ann Bot. 2013 Mar;111(3):385-93. [Content Brief]
[2]. Hsiao YL, et al. Treatment of acute lymphoblastic leukemia from traditional chinese medicine. Evid Based Complement Alternat Med. 2014;2014:601064. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)