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Results for "

Methyl-CpG binding domain protein 2

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-131031
    KCC-07
    1 Publications Verification

    		 DNA Alkylator/Crosslinker Neurological Disease Cancer
    KCC-07 is a potent and brain-penetrant MBD2 (methyl-CpG-binding domain protein 2) inhibitor. KCC-07 prevents binding of MBD2 to methylated DNA and activates brain specific angiogenesis inhibitor 1 (BAI1) inducing anti-proliferative BAI1/p53/p21 signaling . KCC-07 is a TRACER (transcriptional regulation via active control of epigenetic reprogramming) that can stimulate ER transcriptional activity . KCC-07 can be used for the stduy of breast cancer .
    KCC-07
  • HY-179238
    CS-1-103

    		Estrogen Receptor/ERR Cancer
    CS-1-103 is a potent estrogen receptor (ER) TRACER (transcriptional regulation via active control of epigenetic reprogramming). CS-1-103 inhibits ER transcriptional activity with an EC50 of 0.36 μM by recruiting methyl-CpG binding domain protein 2 (MBD2), HDACs and the nucleosome remodeling and deacetylase (NuRD) complex. CS-1-103 can be used for breast and prostate cancer research .
    CS-1-103

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