3 Results for "

MgtA

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "MgtA" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-160202
CAS No.: 115404-77-8
Target:  

Bacterial

Domaines de recherche:  

Infection

18:1 Cardiolipin disodium is a lipid. 18:1 Cardiolipin disodium exhibits functional specificity for MgtA: it maximizes the ATPase activity of MgtA through synergistic binding with Cardiolipin 16:0, and thermostabilizes MgtA. 18:1 Cardiolipin disodium can be used in studies of bacterial infections .
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Cat. No.: HY-139427
CAS No.: 5746-90-7
Pureté:  99.60%
Synonyms: β-Methylglutaconic acid
3-Methylglutaconic acid is the major metabolites accumulating in 3-Methylglutaconic aciduria (MGTA). 3-Methylglutaconic acid can induce lipid oxidative damage and protein oxidative. 3-Methylglutaconic acid decreases the non-enzymatic antioxidant defenses in cerebral cortex supernatants to elicit oxidative stress in the cerebral cortex. 3-Methylglutaconic acid can be used for brain damage disease research .
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Cat. No.: HY-P991294

Target:  

ADC Antibodies

Domaines de recherche:  

Cancer

MGTA-117 is a humanized monoclonal antibody targeting CD117. MGTA-117 can be used for synthesis of antibody-drug conjugate (ADC), utilizing an amanitin payload. MGTA-117 has potent anti-tumor activity and increases survival in three acute myeloid leukemia (AML) xenograft hNSG mice models (Kasumi-1, AML PDX 1 and AML PDX 2). MGTA-117 enables hematopoietic stem cell transplantation (HSCT) preprocessing in AML, myelodysplasia with excess blasts (MDS-EB) and gene therapy .
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