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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10 Results for "
Monocarboxylate transporter MCT4
" in MedChemExpress (MCE) Product Catalog:
Products (10)
10 Results for "Monocarboxylate transporter MCT4" in MCE Product Catalog:
10
10 Publications Verification
Cat. No.: HY-D0067
CAS No.: 50995-74-9
Synonyms: DEAC; Coumarin D 1421; D 1421
Target:
Research Areas:
7ACC1 (DEAC; Coumarin D 1421; D 1421) is a monocarboxylate transporter 1 (MCT-1)/MCT-4 specifc blocker. 7ACC1 attenuates renal cancer cell proliferation, migration, invasion and down-regulates the levels of MCT1/MCT4 expression and extracellular lactate. 7ACC1 is promising for research of cancers .
7
7 Cited Publications
Synonyms: Acriflavinium chloride 3,6-Acridinediamine mix
7
7 Cited Publications
Cat. No.: HY-W088075
CAS No.: 69235-50-3
Synonyms: Acriflavinium chloride hydrochloride
Acriflavine (Acriflavinium chloride) hydrochloride is a fluorescent acridine dye that can be used to label nucleic acid. Acriflavine hydrochloride is an antiseptic agent. Acriflavine hydrochloride is a potent HIF-1 inhibitor that prevents the dimerization of HIF-1α and HIF-1β subunits. Acriflavine hydrochloride inhibits the interaction between monocarboxylate transporter 4 (MCT4) and Basigin. Acriflavine hydrochloride is used in cancer research, such as breast cancer, brain tumor and chronic myeloid leukemia. Acriflavine hydrochloride is a potent papain-like protease (PLpro) inhibitor, which inhibits SARS-CoV-2 .
5
5 Cited Publications
Target:
Research Areas:
BAY-8002 is a potent, selective, orally active inhibitor of monocarboxylate transporter 1 (MCT1), with an IC50 of 85 nM in the MCT1-expressing DLD-1 cells, displays excellent selectivity against MCT4. Anti-tumor activity .
Synonyms: MCT4-IN-1
Target:
Research Areas:
MSC-4381 (MCT4-IN-1), a chemical probe, is an orally active and selective monocarboxylate transporter 4 (MCT4/SLC16A3) inhibitor with an IC50 of 77 nM and a Ki of 11 nM. MSC-4381 targets to the cytosolic domain of MCT4. MSC-4381 results in lactate efflux inhibition and reduction of cellular viability in MCT4 high expressing cells. MSC-4381 has the potential for MCT4 transporter inhibition research . MSC-4381 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Target:
Research Areas:
MCT-IN-1 (Compound 2) is a potent MCT inhibitor, with IC50 values of 9 nM and 14 nM against MCT1 and MCT4, respectively. MCT-IN-1 can be used in research related to solid tumors .
Cat. No.: HY-189476
CAS No.: 2230187-60-5
Target:
Research Areas:
MCT4-IN-2 is an orally active monocarboxylate transporter MCT4 inhibitor. MCT4-IN-2 inhibits the activity of MCT4. MCT4-IN-2 can be used for the research of inflammatory diseases, proliferative diseases and pulmonary fibrosis .
Cat. No.: HY-P87073
Synonyms: MCT 4 antibody; MCT3 antibody; MCT4 antibody; Monocarboxylate transporter 3 antibody; Monocarboxylate transporter 4 antibody; MOT4_HUMAN antibody; SLC16A3 antibody; Solute carrier family 16 member 3 antibody;
Cat. No.: HY-P704180
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: SLC16A3; Solute Carrier Family 16 (Monocarboxylate transporter), Member 3; Solute Carrier Family 16 Member 3; MCT 4; MCT3; Monocarboxylate transporter 3; MCT4; MCT 3; Monocarboxylate transporter 4; MCT-3; Solute Carrier Family 16, Member 3 (Monocarboxylic
Species:
Human
Source:
E. coli Cell-free
Cat. No.: HY-P703259
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: SLC16A3; Solute Carrier Family 16 (Monocarboxylate transporter), Member 3; Solute Carrier Family 16 Member 3; MCT 4; MCT3; Monocarboxylate transporter 3; MCT4; MCT 3; Monocarboxylate transporter 4; MCT-3; Solute Carrier Family 16, Member 3 (Monocarboxylic
Species:
Human
Source:
Sf9 insect cells
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
