1. Metabolic Enzyme/Protease
    Anti-infection
  2. HIF/HIF Prolyl-Hydroxylase
    Bacterial
    SARS-CoV
  3. Acriflavine hydrochloride

Acriflavine hydrochloride (Synonyms: Acriflavinium chloride hydrochloride)

Cat. No.: HY-W088075
Handling Instructions

Acriflavine hydrochloride (Acriflavinium chloride hydrochloride) is a fluorescent acridine dye that can be used to label nucleic acid. Acriflavine hydrochloride is an antiseptic. Acriflavine hydrochloride is a potent HIF-1 inhibitor, with antitumor activity. Acriflavine hydrochloride has antimicrobial and antiviral activities. Acriflavine hydrochloride is a potent papain-like protease (PLpro) inhibitor, which inhibits SARS-CoV-2

For research use only. We do not sell to patients.

Acriflavine hydrochloride Chemical Structure

Acriflavine hydrochloride Chemical Structure

CAS No. : 69235-50-3

Size Price Stock Quantity
500 mg USD 50 In-stock
Estimated Time of Arrival: December 31
1 g   Get quote  
5 g   Get quote  

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Customer Review

Based on 2 publication(s) in Google Scholar

Other Forms of Acriflavine hydrochloride:

Top Publications Citing Use of Products

2 Publications Citing Use of MCE Acriflavine hydrochloride

  • Biological Activity

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  • References

  • Customer Review

Description

Acriflavine hydrochloride (Acriflavinium chloride hydrochloride) is a fluorescent acridine dye that can be used to label nucleic acid[1][2]. Acriflavine hydrochloride is an antiseptic. Acriflavine hydrochloride is a potent HIF-1 inhibitor, with antitumor activity. Acriflavine hydrochloride has antimicrobial and antiviral activities[3][4][5]. Acriflavine hydrochloride is a potent papain-like protease (PLpro) inhibitor, which inhibits SARS-CoV-2[6]

Clinical Trial
Molecular Weight

541.90

Formula

C₂₇H₂₇Cl₃N₆

CAS No.
Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 25 mg/mL (46.13 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8454 mL 9.2268 mL 18.4536 mL
5 mM 0.3691 mL 1.8454 mL 3.6907 mL
10 mM 0.1845 mL 0.9227 mL 1.8454 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: 2.5 mg/mL (4.61 mM); Suspended solution; Need ultrasonic

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: 2.5 mg/mL (4.61 mM); Suspended solution; Need ultrasonic

*All of the co-solvents are provided by MCE.
References
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Product Name:
Acriflavine hydrochloride
Cat. No.:
HY-W088075
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