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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
9 Results for "
N-Deacetylcolchicine
" in MedChemExpress (MCE) Product Catalog:
Products (9)
9 Results for "N-Deacetylcolchicine" in MCE Product Catalog:
Research Areas:
N-Deacetylcolchicine is a microtubule polymerization inhibitor with an IC50 of 3 μM against bovine brain microtubules. N-Deacetylcolchicine is a derivative of Colchicine (HY-16569). N-Deacetylcolchicine can activate the GTPase activity of microtubules and can be used for the research of cancer .
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4 Cited Publications
Cat. No.: HY-P2161B
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Cat. No.: HY-P5544
CAS No.: 60230-21-9
Synonyms: N-Acetylmuramyl-L-Ala-γ-D-Glu-meso-diaminopimelic acid
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Cat. No.: HY-121434A
CAS No.: 49720-72-1
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N-Deacetylcolchicine tartrate is a microtubule polymerization inhibitor with an IC50 of 3 μM against bovine brain microtubules. N-Deacetylcolchicine tartrate is a derivative of Colchicine (HY-16569). N-Deacetylcolchicine tartrate can activate the GTPase activity of microtubules and can be used for the research of cancer .
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N-Deacetyl-N-formylcolchicine (N-Formyl-N-deacetylcolchicine, Compound 11) is a selective inhibitor targeting the colchicine-binding site of tubulin. N-Deacetyl-N-formylcolchicine shows antiproliferative activity against various cancer cell lines with IC50 values of 32.61-100.28 nM. N-Deacetyl-N-formylcolchicine inhibits microtubule polymerization to block cell division, induces cancer cell apoptosis and suppresses migration. N-Deacetyl-N-formylcolchicine is promising for research of cancers such as lung cancer and various solid tumors .
Cat. No.: HY-P2161
CAS No.: 872719-49-8
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Cat. No.: HY-P2115
CAS No.: 127932-90-5
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Cat. No.: HY-P5544A
Synonyms: N-Acetylmuramyl-L-Ala-γ-D-Glu-meso-diaminopimelic acid TFA
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Cat. No.: HY-P2161A
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
