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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
NADPH-dependent metabolism
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "NADPH-dependent metabolism" in MCE Product Catalog:
Target:
Cat. No.: HY-117806
CAS No.: 1388225-79-3
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TSR-011-isomer is an isomer of Belizatinib (HY-17603), a ALK inhibitor with an IC50 of 6 nM. TSR-011-isomer acts as a substrate for metabolic hydrolysis and NADPH-dependent metabolism. TSR-011-isomer undergoes enzymatic hydrolysis in mouse plasma and NADPH-dependent metabolism in mouse liver microsomes, thereby supporting clearance processes. TSR-011-isomer can be used in studies related to ALK-driven cancers .
Cat. No.: HY-E71567
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2-Hydroxymethylglutarate dehydrogenase (EC 1.1.1.291) is an NADPH-dependent D-ribulose reductase—a type of oxidoreductase—that catalyzes the reduction of D-ribulose to D-arabitol. It plays a key role in pentose metabolism, sugar alcohol metabolism, and carbon source utilization in microorganisms and fungi.
Cat. No.: HY-E71772A
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3-Oxo-5-β-steroid 4-dehydrogenase from human (Recombinant) (EC 1.3.1.3) belongs to the NADPH-dependent short-chain dehydrogenase/reductase superfamily (AKR family). It catalyzes the 5β-reduction of the Δ4 double bond in steroid molecules and is involved in bile acid synthesis and steroid hormone metabolism, serving as a crucial enzyme for maintaining hepatic cholesterol metabolism and endocrine homeostasis.
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L-Lactaldehyde ((2S)-Hydroxypropanal) is a chiral aldehyde, metabolic intermediate, and enzyme substrate. L-Lactaldehyde is oxidized to L-lactate by NAD-dependent lactaldehyde dehydrogenase. L-Lactaldehyde is reduced to L-1,2-propanediol by NADH/NADPH-dependent oxidoreductases. L-Lactaldehyde is used in studies of microbial sugar metabolism and carbonyl metabolism .
Cat. No.: HY-122940R
CAS No.: 644-06-4
Synonyms: Ageratochromene (Standard)
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
