2 Results for "

NOD1 and NOD2 responses

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "NOD1 and NOD2 responses" in MCE Product Catalog:

Cat. No.: HY-123924
CAS No.: 2244984-64-1
Target:  

RIP kinase

Research Areas:  

Inflammation/Immunology

CSLP37 is a selective RIPK2 inhibitor with an IC50 of 16.3 nM. CSLP37 shows no inhibitory activity against RIPK1 and RIPK3. CSLP37 displays potent suppression of cellular NOD1 and NOD2 responses .
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Cat. No.: HY-168024
NOD1/2-IN-1 (Compound 18) is a potent RIPK2 inhibitor with an IC50 value of 1.4 nM, as determined by the ADP-Glo assay. NOD1/2-IN-1 blocks the production of pro-inflammatory cytokines by inhibiting the NOD1/NOD2 pathways, with IC50 values of 18 nM and 170 nM for NOD1 and NOD2, respectively, thereby reducing inflammatory responses. NOD1/2-IN-1 can be used in studies related to colitis .
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