NOD1/2-IN-1
NOD1/2-IN-1 (Compound 18) is a potent RIPK2 inhibitor with an IC50 value of 1.4 nM, as determined by the ADP-Glo assay. NOD1/2-IN-1 blocks the production of pro-inflammatory cytokines by inhibiting the NOD1/NOD2 pathways, with IC50 values of 18 nM and 170 nM for NOD1 and NOD2, respectively, thereby reducing inflammatory responses. NOD1/2-IN-1 can be used in studies related to colitis.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C22H25N5O2S
- Molecular Weight:423.53
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
- Protokoll
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
Beschreibung
IC50 & Target
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NOD1 18 nM (IC50) |
NOD2 170 nM (IC50) |
Chemical Information
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Molecular Weight 423.53
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Formel C22H25N5O2S
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SMILES
COC1=CC2=C(C=C1OCCN(CC)CC)N=CN=C2NC3=CC=C4SC=NC4=C3
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
NOD1/2-IN-1 Related Classifications
HY-168024 Related Classifications
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