2 Results for "

NP1 peptide

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "NP1 peptide" in MCE Product Catalog:

製品番号: HY-P12278
Target:  

EGFR

研究分野:  

Cancer

NP1 peptide is a cyclic peptide (CHSHGTRAC) and TK-EGFR inhibitor (IC50 = 0.58 nM, Kd = 18.40 μM). NP1 peptide blocks kinase activity by binding to the ATP-binding pocket of TK-EGFR and inhibits autophosphorylation at the EGFR Y1173 site, and it also serves as a pH-responsive nanocarrier for siRNA delivery. NP1 peptide is used in cancer research .
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製品番号: HY-P11859
研究分野:  

Cancer

NP1 is a NOTA-chelated linear precursor based on the ROR1-targeting peptide. After labeling with [ 18F]AlF, NP1 yields [ 18F]AlF-NP1, a PET imaging probe with excellent ROR1 specificity (KD = 141.7 nM), rapid tumor uptake and high target-to-background ratio, which is suitable for non-invasive visualization of various ROR1-overexpressing tumors .
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