2 Results for "

Nepaprazole sodium

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Nepaprazole sodium" in MCE Product Catalog:

Cat. No.: HY-19153A
CAS No.: 157564-11-9
Synonyms: rel-TY-11345
Target:  

Proton Pump

Research Areas:  

Inflammation/Immunology

Nepaprazole sodium (rel-TY-11345) is a proton pump H+/K+-ATPase inhibitor. Nepaprazole sodium inhibits H+/K+-ATPase activity in rabbit gastric mucosal microsomes, with IC50 values of 5.8 μM and 9.9 μM at pH 6.0 and pH 7.4, respectively, and its inhibitory activity is enhanced under weakly acidic conditions. Nepaprazole sodium inhibits basal and Tetragastrin (HY-125556)-stimulated gastric acid secretion. Nepaprazole sodium can be used in studies on gastric proton pump function, gastric acid secretion, and mechanisms related to peptic ulcers .
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Cat. No.: HY-19153
CAS No.: 156601-79-5
Synonyms: rel-TY-11345 free base
Target:  

Proton Pump

Research Areas:  

Inflammation/Immunology

Nepaprazole (rel-TY-11345 free base) is a proton pump inhibitor. Nepaprazole inhibits H +/K +-ATPase activity in isolated rabbit gastric mucosal microsomes with the IC50 values of 5.8 μM and 9.9 μM at pH 6.0 and pH 7.4, respectively. Nepaprazole can be used for study of peptic ulcer diseases .
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