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Cat. No.: HY-19153

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Nepaprazole

(Synonyms: rel-TY-11345 free base)

Nepaprazole (rel-TY-11345 free base) is a proton pump inhibitor. Nepaprazole inhibits H⁺/K⁺-ATPase activity in isolated rabbit gastric mucosal microsomes with the IC₅₀ values of 5.8 μM and 9.9 μM at pH 6.0 and pH 7.4, respectively. Nepaprazole can be used for study of peptic ulcer diseases.

For research use only. We do not sell to patients.

CAS No.: 156601-79-5
Formula: C₁₈H₁₉N₃O₂S
Molecular Weight:341.43

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

Nepaprazole Chemical Structure

CAS No.: 156601-79-5

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Chemical Information

CAS No. 156601-79-5
Molecular Weight 341.43
Formula C₁₈H₁₉N₃O₂S
SMILES

O=S(C1=NC2=CC=CC=C2N1)[C@@]3([H])C4=NC=CC(OC)=C4CCCC3
Synonyms

rel-TY-11345 free base
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Yamaguchi T, et al. Biochemical and pharmacological properties of a newly synthesized proton pump (H+/K(+)-ATPase) inhibitor, TY-11345 in experimental animals. Jpn J Pharmacol. 1993;62(4):363-371. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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