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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
90 Results for "
Nuclear factor-kappa B
" in MedChemExpress (MCE) Product Catalog:
Products (90)
90 Results for "Nuclear factor-kappa B" in MCE Product Catalog:
17
17 Publications Verification
Cat. No.: HY-P7425
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF11; Tumor Necrosis factor (Ligand) Superfamily, Member 11; TNF Superfamily Member 11; Receptor Activator Of Nuclear factor kappa-B Ligand; TRANCE; TNLG6B; RANKL; Receptor Activator Of Nuclear factor kappa B Ligand; OPGL; Tumor Necrosis factor Ligand
10
10 Cited Publications
Cat. No.: HY-P7424
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF11; Tumor Necrosis factor (Ligand) Superfamily, Member 11; TNF Superfamily Member 11; Receptor Activator Of Nuclear factor kappa-B Ligand; TRANCE; TNLG6B; RANKL; Receptor Activator Of Nuclear factor kappa B Ligand; OPGL; Tumor Necrosis factor Ligand
6
6 Cited Publications
Cat. No.: HY-P73388
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF11; Tumor Necrosis factor (Ligand) Superfamily, Member 11; TNF Superfamily Member 11; Receptor Activator Of Nuclear factor kappa-B Ligand; TRANCE; TNLG6B; RANKL; Receptor Activator Of Nuclear factor kappa B Ligand; OPGL; Tumor Necrosis factor Ligand
4
4 Cited Publications
Cat. No.: HY-P73386
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF11; Tumor Necrosis factor (Ligand) Superfamily, Member 11; TNF Superfamily Member 11; Receptor Activator Of Nuclear factor kappa-B Ligand; TRANCE; TNLG6B; RANKL; Receptor Activator Of Nuclear factor kappa B Ligand; OPGL; Tumor Necrosis factor Ligand
3
Target:
Research Areas:
3
Category:
Infection Colophony Pinaceae Ketones, Aldehydes, Acids Metabolic Disease Plants Disease Research Fields Inflammation/Immunology
Target:
3
3 Cited Publications
Cat. No.: HY-P9958A
CAS No.: 615258-40-7
Target:
Research Areas:
3
3 Cited Publications
Cat. No.: HY-N2106
CAS No.: 67909-49-3
Category:
Alkaloids Evodia rutaecarpa (Juss.) Benth. Rutaceae Plants Disease Research Fields Inflammation/Immunology Indole Alkaloids
Target:
3
3 Cited Publications
Cat. No.: HY-P73681
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: RELA; NF-kappa-B Transcription factor P65; Prev. NFKB3; P65 Iso5 Isoform Delta 10; Nuclear factor Of kappa Light Polypeptide Gene Enhancer In B-Cells 3; Alternative Protein RELA; P65; NF-kappa-B P65delta3; V-Rel Avian Reticuloendotheliosis Viral Oncogene
3
3 Cited Publications
Cat. No.: HY-P81238
Synonyms: Phospho-NF-KB p65 (Ser536) ;
NF-kB p65 (phospho S536); p-NF-κB p65(Phospho-Ser536); RELA(phospho S536); NF kB P65; NF-kB p65; NFKBp65; NF-κBp65; p65 NF kappaB; p65 NFkB; NFKBp65; RELA; Transcription factor p65; v rel avian reticuloendotheliosis viral oncogene homolog A (Nuclear factor of kappa light polypeptide gene enhancer in B cells 3 (p65)); V Rel Avian Reticuloendotheliosis Viral Oncogene Homolog A; v rel reticuloendotheliosis viral oncogene homolog A (avian); v-rel reticuloendotheliosis viral oncogene homolog A; p65NFKB; Avian reticuloendotheliosis viral (v rel) oncogene homolog A; MGC131774; NFKB 3; NFKB3; Nuclear factor NF kappa B p65 Subunit; Nuclear factor of kappa light polypeptide gene enhancer in B cells 3; Nuclear factor Of kappa Light Polypeptide Gene Enhancer In B Cells; TF65_HUMAN. NFκB-p65; NFκB p65; NF κB-p65; NFκBp65;
2
2 Cited Publications
Cat. No.: HY-N0632
CAS No.: 65497-07-6
2
1
Research Areas:
Flumethasone (Flumetasone) is an orally active, high selective and potent glucocorticoid receptor (GR) agonist. Flumethasone activates GR to inhibit nuclear factor kappa B (NF-κB)-mediated pro-inflammatory cytokine production (TNF-α, IL-1β) and promotes anti-inflammatory gene expression (IL-10), while also regulating metabolic enzyme activity (tyrosine aminotransferase induction). Flumethasone is promising for research of inflammatory diseases, cancer, and endocrine regulation .
1
1 Cited Publications
Cat. No.: HY-P701786
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IKBKB; IKK-2; Inhibitor Of Nuclear factor kappa B Kinase Subunit Beta; CDNA FLJ33978 Fis, Clone DFNES2004354, Highly Similar To Inhibitor Of Nuclear factor kappa B Kinase Subunit Beta; IKK-Beta; Inhibitor Of kappa Light Polypeptide Gene Enhancer In B-Cell
Species:
Source:
1
1 Cited Publications
Cat. No.: HY-P700226AF
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF11; Tumor Necrosis factor (Ligand) Superfamily, Member 11; TNF Superfamily Member 11; Receptor Activator Of Nuclear factor kappa-B Ligand; TRANCE; TNLG6B; RANKL; Receptor Activator Of Nuclear factor kappa B Ligand; OPGL; Tumor Necrosis factor Ligand
1
1 Cited Publications
Cat. No.: HY-P7425B
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF11; Tumor Necrosis factor (Ligand) Superfamily, Member 11; TNF Superfamily Member 11; Receptor Activator Of Nuclear factor kappa-B Ligand; TRANCE; TNLG6B; RANKL; Receptor Activator Of Nuclear factor kappa B Ligand; OPGL; Tumor Necrosis factor Ligand
1
1 Cited Publications
Cat. No.: HY-P81124
Synonyms: OPGL; CD254; hRANKL2; ODF; OPGL; Osteoclast differentiation factor; Osteoprotegerin ligand; RANKL; Receptor activator of Nuclear factor kappa B ligand; sOdf; SOFA; TNF related activation induced cytokine; TNFSF 11; TNFSF11; TRANCE; Tumor necrosis factor ligand superfamily member 11; Osteoprotegerin Ligand; TNF11_HUMAN.
Cat. No.: HY-N2056
CAS No.: 17019-92-0
Synonyms: 11-Keto-β-boswellic acid
Category:
Triterpenes Terpenoids Boswellia serrata Plants Burseraceae Disease Research Fields Cancer
Target:
Cat. No.: HY-175703
CAS No.: 3108878-05-0
Research Areas:
RANKL-IN-1 is a selective and orally active Receptor Activator of Nuclear Factor-κ B Ligand (RANKL) inhibitor with a KD value of 7.6 μM. RANKL-IN-1 exhibits inhibitory activity and selectivity against osteoclastogenesis with an IC50 value of 0.07 μM and SI of 82.57. RANKL-IN-1binds directly to RANKL and blocks the RANKL-induced activation of the NF-κB and MAPK pathways. RANKL-IN-1 can be used for the research of metabolic disease, such as osteoporosis .
Cat. No.: HY-174569
Target:
Research Areas:
Human NFKB1 mRNA encodes the human nuclear factor kappa B subunit 1 (NFKB1) protein, a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. NFKB is a critical regulator of the immediate-early response to viral infection.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
