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Nucleoside diphosphate kinase

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製品番号 製品名 Target 研究分野 構造式
  • HY-P2881
    Nucleoside diphosphate kinase

    Nucleoside 5′-diphosphate kinase

    		 Biochemical Assay Reagents Cancer
    Nucleoside diphosphate kinase (Nucleoside 5′-diphosphate kinase) belongs to the family of structurally and functionally conserved NDPK (Nucleotide diphosphate kinase) enzymes. Nucleoside diphosphate kinase catalyzes the reversible transfer of γ-phosphates between nucleoside di-(NDP) and triphosphates (NTP) through ping-pong bi-bi reaction kinetics. Nucleoside diphosphate kinase is the essential housekeeping proteins that produces CTP (cytidine triphosphate) for lipid syntheses, UTP (Uridine triphosphate) for polysaccharide syntheses, and GTP (guanosine triphosphate) for protein syntheses, signal transduction, and microtubules polymerization .
    Nucleoside diphosphate kinase
  • HY-E70108
    Cytidylate kinase

    		PKC Others
    Cytidylate kinase catalyzes the phosphoryl transfer from ATP to CMP and dCMP, resulting in the formation nucleoside diphosphates .
    Cytidylate kinase
  • HY-165154
    Cyclamidomycin

    Desdanine; Pyracrimycin A

    		 Antibiotic Bacterial Fungal Pyruvate Kinase Oxidative Phosphorylation Infection Inflammation/Immunology
    Cyclamidomycin (Desdanine) is an acrylamide antibiotic with antibacterial activity. Cyclamidomycin inhibits nucleoside diphosphate kinase and pyruvate kinase (in E. coli) and oxidative phosphorylation in rat liver mitochondria. Cyclamidomycin is active against S. aureus, M. flavus, S. lutea, B. subtilis, E. coli, S. flexneri, S. typhosa, P. vulgaris, and K. pneumoniae (MICs=3.12-25 mg/ml) .
    Cyclamidomycin
  • HY-171362A
    PSI-7410 sodium

    		Drug Metabolite Infection
    PSI-7410 sodium is the ametabolite of Sofosbuvir (HY-15005). PSI-7410 sodium can be metabolized to PSI-7409 (HY-15745) by nucleoside diphosphate kinase. PSI-7410 sodium is promising for research of anti-hepatitis C agent .
    PSI-7410 sodium
  • HY-E71013
    Nucleoside monophosphate kinase, Bovine

    		Endogenous Metabolite Metabolic Disease
    Nucleoside monophosphate kinase, Bovine (EC 2.7.4.6) is an enzymes that catalyze the exchange of phosphate groups between different nucleoside diphosphates. Nucleoside monophosphate kinase, Bovine (EC 2.7.4.6) activities maintain an equilibrium between the concentrations of different nucleoside triphosphates such as, for example, when GTP produced in the citric acid (Krebs) cycle is converted to ATP.
    Nucleoside monophosphate kinase, Bovine
  • HY-134278A
    8-Bromoinosine-5'-O-triphosphate tetrasodium

    8-Br-ITP tetrasodium; 8-Bromo ITP tetrasodium

    		 Nucleoside Antimetabolite/Analog Others
    8-Bromoinosine-5'-O-triphosphate (8-Br-ITP) tetrasodium is a derivative of the nucleoside triphosphate Inosine-5'-triphosphate (ITP) (HY-W013706). 8-Bromoinosine-5'-O-triphosphate tetrasodium can be used in the determination of nucleoside diphosphate kinase (NDPK) activity .
    8-Bromoinosine-5'-O-triphosphate tetrasodium

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