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Results for "

Oxalate Oxidase

" in MedChemExpress (MCE) Product Catalog:

8

Inhibitors & Agonists

1

Biochemical Assay Reagents

2

Oligonucleotides

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-132588
    Lumasiran

    ALN-G01

    		 Small Interfering RNA (siRNA) Glycolate Oxidase Metabolic Disease
    Lumasiran (ALN-G01), a siRNA product, reduces hepatic oxalate production by targeting glycolate oxidase. By silencing the gene encoding glycolate oxidase, Lumasiran depletes glycolate oxidase and thereby inhibits the synthesis of oxalate, which is the toxic metabolite that is directly associated with the clinical manifestations of Primary hyperoxaluria type 1 (PH1) .
    Lumasiran
  • HY-132613
    Lumasiran sodium

    		Small Interfering RNA (siRNA) Glycolate Oxidase Metabolic Disease
    Lumasiran sodium, an investigational RNA interference (RNAi) therapeutic agent, reduces hepatic oxalate production by targeting glycolate oxidase. Lumasiran sodium reduces urinary oxalate excretion, the cause of progressive kidney failure in primary hyperoxaluria type 1 (PH1) .
    Lumasiran sodium
  • HY-E70385
    Oxalate Oxidase

    		Endogenous Metabolite Others
    Oxalate Oxidase, or oxalate oxidase, catalyzes the oxidation of oxalic acid to hydrogen peroxide and carbon dioxide in the presence of oxygen. Oxalate Oxidase can be found in a variety of plants (such as barley) and microorganisms and can be used to treat wastewater and filtrates containing oxalic acid .
    Oxalate Oxidase
  • HY-W088011B
    Sodium glycolate, 98%

    Sodium hydroxyacetate, 98%

    		 Lactate Dehydrogenase Aminotransferases (Transaminases) Endocrinology
    Sodium glycolate, 98% (Sodium hydroxyacetate, 98%) is an orally active, versatile organic salt . Sodium glycolate, 98% acts as an enzyme activity regulator that increases the activities of glycolate oxidase (GAO) and lactate dehydrogenase (LDH), while reducing the activity of glycolate dehydrogenase (GAD). Sodium glycolate, 98% induces oxalate biosynthesis and causes hyperoxaluria in rats. Sodium glycolate, 98% reduces urinary calcium excretion in male albino rats. Sodium glycolate, 98% can be used in studies related to calcium oxalate urolithiasis and hyperoxaluria .
    Sodium glycolate, 98%
  • HY-148610
    LDH-IN-2

    		Others Metabolic Disease
    LDH-IN-2, a salicylic acid derivative, is an inhibitor of glycolate oxidase (GO). LDH-IN-2 decreases oxalate output in hyperoxaluric hepatocytes. LDH-IN-2 can be used for research of primary hyperoxaluria type 1 (PH1) .
    LDH-IN-2
  • HY-W176012
    Glycolate oxidase-IN-1

    		Others Metabolic Disease
    Glycolate oxidase-IN-1(compound 26), a salicylic acid derivative, is a glycolate oxidase (GO) inhibitor with an IC50 of 38.2 μM. Glycolate oxidase-IN-1 has the ability to reduce oxalate production in hyperoxalate hepatocytes and can be used in the study of primary hyperoxaluria type 1 (PH1) .
    Glycolate oxidase-IN-1
  • HY-E70385A
    Oxalate oxidase, B. subtilis

    		Endogenous Metabolite Metabolic Disease
    Oxalate oxidase, B. subtilis (EC 1.2.3.4) is a redox enzyme that acts on the donor aldehyde or carbonyl group, using oxygen as the acceptor. Oxalate oxidase, B is involved in the metabolism of glyoxylate and dicarboxylic acids. Oxalate oxidase, B has two cofactors: FAD and manganese. Oxalate oxidase, B has three substrates: oxalic acid, O2, and H +, and two products: CO2 and H2O2.
    Oxalate oxidase, B. subtilis
  • HY-180992
    Dual GO/LDHA-IN-1

    		Lactate Dehydrogenase Metabolic Disease
    Dual GO/LDHA-IN-1 is an orally available dual inhibitor targeting glycolate oxidase (GO) and lactate dehydrogenase A (LDHA), with Ki values of 390 nM and 40 nM, respectively. Dual GO/LDHA-IN-1 reduces hepatic LDHA levels, urinary oxalate excretion, and renal calcium-oxalate crystal deposition. Dual GO/LDHA-IN-1 is applicable for research on primary hyperoxaluria type 1 .
    Dual GO/LDHA-IN-1

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