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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
P2X7 purinergic receptor
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "P2X7 purinergic receptor" in MCE Product Catalog:
Synonyms: 7-Desacetoxy-6,7-dehydrogedunin
Target:
PERK Prokineticin Receptor P2X Receptor Caspase NOD-like Receptor (NLR) Pyroptosis Tyrosinase
Research Areas:
Neurological Disease Metabolic Disease Inflammation/Immunology
7DG (7-Desacetoxy-6,7-dehydrogedunin) is a PKR inhibitor, P2X7 purinergic receptor inhibitor, and skin-lightening agent. 7DG binds outside the ATP-catalytic domain of PKR, blocks the kinase activity-independent protein-protein interactions of PKR, inhibits the phosphorylation and activity of PKR, disrupts ASC assembly and caspase-1 activation, and suppresses the activation of the NLRP1 inflammasome. 7DG inhibits pyroptosis, suppresses the ATP-P2X7 signaling pathway, and abolishes ATP-induced increases in the expression levels of MITF, tyrosinase, PMEL/gp100, and melanin content. 7DG exerts skin-lightening effects in cultured skin in vitro. 7DG can be used in research related to chronic obstructive pulmonary disease, gout, type 2 diabetes, Alzheimer's disease, and hyperpigmentary skin disorders .
Cat. No.: HY-19427
CAS No.: 345304-65-6
Target:
Research Areas:
AZD9056 is a P2X7 purinergic receptor antagonist with anticancer activity. AZD9056 can inhibit the invasion and metastasis of cancer stem cells .
Cat. No.: HY-P705903
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: P2RX7; purinergic receptor P2X, Ligand Gated Ion Channel, 7; purinergic receptor P2X 7; purinergic receptor P2X7; P2X7; purinergic receptor; Purnergic receptor P2X 7; P2X Purinoceptor; P2X Purinoceptor 7; P2X7 Isoform Q; ATP receptor; P2X7 Isoform O; P2Z receptor; P2X7 Isoform N; MGC20089; P2X7 receptor; purinergic receptor P2X, Ligand-Gated Ion Channel, 7
Species:
Human
Source:
E. coli
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
