1 Result for "

PARP1/c-Met-IN-1

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "PARP1/c-Met-IN-1" in MCE Product Catalog:

Cat. No.: HY-161372
CAS No.: 2944101-99-7
Target:  

PARP c-Met/HGFR Apoptosis

Research Areas:  

Cancer

PARP1/c-Met-IN-1 (Compound 16) is a selective dual inhibitor for PARP1 and c-Met, with IC50s of 3.3 and 32.2 nM, respectively. PARP1/c-Met-IN-1 induces cell apoptosis and cell cycle arrest in G2/M phase in MDA-MB-231 cells. PARP1/c-Met-IN-1 exhibits antitumor activity in mice [1].
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