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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
147 Results for "
PD-1/PD-L1-IN-29 intermediate-1
" in MedChemExpress (MCE) Product Catalog:
Products (147)
147 Results for "PD-1/PD-L1-IN-29 intermediate-1" in MCE Product Catalog:
2
2 Cited Publications
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PAR-2-IN intermediate-1 is a drug intermediate that can be used to synthesize inhibitors of the PAR-2 signaling pathway .
Cat. No.: HY-42487
CAS No.: 110351-94-5
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Exatecan Intermediate 1 (compound 6) is an intermediate of Exatecan (HY-13631). Exatecan is a DNA topoisomerase I inhibitor with anticancer effects .
Cat. No.: HY-W021377
CAS No.: 182182-31-6
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Exatecan Intermediate 2 (Compound B) is an intermediate of Exatecan (DX-8951, HY-13631). Exatecan is an anticancer agent belonging to the class of camptothecin analogs. Exatecan interferes with the proliferation and division of tumor cells by interacting with DNA, thereby inhibiting tumor growth. Exatecan is primarily used for research of a variety of cancers including ovarian, lung and breast cancers .
Cat. No.: HY-44369
CAS No.: 143655-58-7
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Exatecan Intermediate 6 is the intermediate of Exatecan (HY-13631) And Exatecan (DX-8951) is a DNA topoisomerase I inhibitor with an IC50 value of 2.2 μM (0.975 μg/mL) that can be used in cancer research. Exatecan Intermediate 6 can be used to synthesize Antibody-Drug Conjugates (ADCs).
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GPX4-IN-1 intermediate-1 is a Drug Intermediate that can be used in organic synthesis-related research. GPX4-IN-1 intermediate-1 participates in the synthesis of GPX4-IN-1 (HY-138544), and GPX4-IN-1 can be applied in cancer-related research .
Cat. No.: HY-42487B
CAS No.: 110351-91-2
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(R)-Exatecan Intermediate 1 is a key intermediate in the synthesis of Camptothecin (HY-16560) derivatives, and can be used to prepare Exatecan mesylate (DX8951f) (HY-13631A). (R)-Exatecan Intermediate 1 enables the synthesis of Exatecan, which exhibits low sensitivity to multidrug resistance and has great value in anti-tumor research .
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Dolutegravir intermediate-1 (Compound 11) is a synthetic intermediate. Dolutegravir intermediate-1 can be used to synthesize Dolutegravir (HY-13238). Dolutegravir is an Integrase inhibitor with potential applications in HIV-1 infection research .
Cat. No.: HY-43565
CAS No.: 2290562-59-1
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Exatecan intermediate 9 is an intermediate for the synthesis of Exatecan (HY-13631). Exatecan (DX-8951) is a common toxin component in ADC preparation (ADC Cytotoxin) and an inhibitor of DNA topoisomerase I (IC50=2.2 μM) .
Cat. No.: HY-42487S
CAS No.: 1346617-23-9
Cat. No.: HY-33048
CAS No.: 120205-48-3
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Monomethyl auristatin E intermediate-1 is an intermediate reagent in the synthesis of Monomethyl auristatin E (HY-15162). Monomethyl auristatin E (MMAE) is a microtubule/tubulin inhibitor with anticancer activity. MMAE is widely used as the cytotoxic component (ADC Cytotoxin) of antibody-drug conjugates (ADCs) .
Cat. No.: HY-W021377B
CAS No.: 2436720-50-0
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Exatecan Intermediate 4 (Compound 14f) is an intermediate of Exatecan (DX-8951, HY-13631). Exatecan is an anticancer agent belonging to the class of camptothecin analogs. Exatecan interferes with the proliferation and division of tumor cells by interacting with DNA, thereby inhibiting tumor growth. Exatecan is primarily used for research of a variety of cancers including ovarian, lung and breast cancers .
Cat. No.: HY-20588
CAS No.: 123066-64-8
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CRAC intermediate 2 (the starting compound in example 23) is an intermediate. CRAC intermediate 2 can be used in the research of CRAC inhibitors .
Cat. No.: HY-77016
CAS No.: 174775-48-5
Synonyms: Vilazodone intermediate 5
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Ethyl 5-aminobenzofuran-2-carboxylate (Vilazodone Intermediate 5) is a drug intermediate for synthesis of various active compounds.
Cat. No.: HY-W021377A
CAS No.: 2437603-23-9
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Exatecan Intermediate 2 hydrochloride (Compound B) is an intermediate of Exatecan (DX-8951, HY-13631). Exatecan is an anticancer agent belonging to the class of camptothecin analogs. Exatecan interferes with the proliferation and division of tumor cells by interacting with DNA, thereby inhibiting tumor growth. Exatecan is primarily used for research of a variety of cancers including ovarian, lung and breast cancers .
Cat. No.: HY-I0510
CAS No.: 868540-16-3
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Carfilzomib intermediate-1 (Intermediate IV) is a key intermediate for Carfilzomib (HY-10455) synthesis .
Cat. No.: HY-404046
CAS No.: 2417310-51-9
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GS-1427 intermediate-1 is a key intermediate in the synthesis of GS-1427 (HY-175745) .
Cat. No.: HY-41071
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(6R)-Taltobulin intermediate-9 is an intermediate in the synthesis of Taltobulin (HY-15584) .
Cat. No.: HY-41047
CAS No.: 228266-38-4
Taltobulin intermediate-1 is an intermediate in the synthesis of Taltobulin (HY-15584). Taltobulin is a common toxin component in ADC preparation (ADC Cytotoxin), and it is also a powerful tubulin (Microtubule/Tubulin) inhibitor. Taltobulin disrupts tubulin polymerization, induces mitotic arrest, and induces apoptosis .
Cat. No.: HY-41054
CAS No.: 610786-69-1
Taltobulin intermediate-3 is an intermediate in the synthesis of Taltobulin (HY-15584). Taltobulin is a common toxin component in ADC preparation (ADC Cytotoxin), and it is also a powerful tubulin (Microtubule/Tubulin) inhibitor. Taltobulin disrupts tubulin polymerization, induces mitotic arrest, and induces apoptosis .
Cat. No.: HY-402091
CAS No.: 232931-64-5
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SJG-136 intermediate-1 (compound 19) is an intermediate for synthesizing SJG-136. SJG-136 is a DNA cross-linking agent, with an XL50 of 45 nM for pBR322 DNA .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
