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Cat. No.: HY-402091

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SJG-136 intermediate-1

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SJG-136 intermediate-1 (compound 19) is an intermediate for synthesizing SJG-136. SJG-136 is a DNA cross-linking agent, with an XL₅₀ of 45 nM for pBR322 DNA.

For research use only. We do not sell to patients.

Purity: 99.95%
CAS No.: 232931-64-5
Formula: C₃₉H₄₄N₄O₁₂
Molecular Weight:760.79

Storage:

Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month

SJG-136 intermediate-1 Chemical Structure

CAS No.: 232931-64-5

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One-stop CDMO Service

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Biological Activity

Description

SJG-136 intermediate-1 (compound 19) is an intermediate for synthesizing SJG-136. SJG-136 is a DNA cross-linking agent, with an XL₅₀ of 45 nM for pBR322 DNA^[1].

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Chemical Information

CAS No. 232931-64-5
Appearance Solid
Molecular Weight 760.79
Formula C₃₉H₄₄N₄O₁₂
Color White to off-white
SMILES

C=CCOC(N1C2=CC(OCCCOC3=C(OC)C=C(C(N4[C@](CC(C4)=C)([H])[C@@H](N5C(OCC=C)=O)O)=O)C5=C3)=C(OC)C=C2C(N6[C@](CC(C6)=C)([H])[C@@H]1O)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. S J Gregson, et al. Design, synthesis, and evaluation of a novel pyrrolobenzodiazepine DNA-interactive agent with highly efficient cross-linking ability and potent cytotoxicity. J Med Chem. 2001 Mar 1;44(5):737-48. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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SJG-136 intermediate-1

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Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

SJG-136 intermediate-1 Related Classifications

HY-402091 Related Classifications