1 Result for "

PROTAC BRD4 Degrader-40

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "PROTAC BRD4 Degrader-40" in MCE Product Catalog:

Cat. No.: HY-177730
Research Areas:  

Cancer

PROTAC BRD4 Degrader-40 is a BRD4 PROTAC degrader. PROTAC BRD4 Degrader-40 binds to Cereblon and recruits the CRL4 CRBN E3 ubiquitin ligase complex, mediates BRD4 degradation via the ubiquitin-proteasome pathway, and does not induce the degradation of classic CRBN neo-substrates IKZF1 and IKZF3. PROTAC BRD4 Degrader-40 induces BRD4 degradation in cancer cells. PROTAC BRD4 Degrader-40 can be used in research related to diffuse large B-cell lymphoma and acute myeloid leukemia .
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