PROTAC BRD4 Degrader-40
PROTAC BRD4 Degrader-40 is a Bromodomain protein 4 (BRD4) PROTAC degrader. PROTAC BRD4 Degrader-40 can induce BRD4 degradation in cancer cells. PROTAC BRD4 Degrader-40 can be used for the research of cancer, such as leukemia.
(Pink: BRD4 ligand (HY-78695); Blue: Cereblon ligand (HY-163927); Black: linker).
For research use only. We do not sell to patients.
- Formula: C39H34ClN9O4S
- Molecular Weight:760.26
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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BRD4 |
Cereblon |
PROTAC BRD4 Degrader-40 (Compound 5Y-3) (0.1-1 μM, 24 h) induces BRD4 degradation in SUDHL-4 and MV-4-11 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:SUDHL-4 and MV-4-11 cells
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Concentration:0.1 and 1 μM
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Incubation Time:24 h
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Result:Reduced BRD4 levels.
Chemical Information
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Molecular Weight 760.26
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Formula C39H34ClN9O4S
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SMILES
O=C(N/N=C\C1=CC=C(C2=C(N3C)C(N(C(CC4)C(NC4=O)=O)C3=O)=CC=C2)C=C1)C[C@H]5C6=NN=C(C)N6C7=C(C(C)=C(C)S7)C(C8=CC=C(Cl)C=C8)=N5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PROTAC BRD4 Degrader-40 Related Classifications
HY-177730 Related Classifications
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