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3 Results for "
PROTAC SGK3 degrader-2
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "PROTAC SGK3 degrader-2" in MCE Product Catalog:
Cat. No.: HY-176823
CAS No.: 2381196-78-5
PROTAC SGK3 degrader-2 is the cis epimer of PROTAC SGK3 degrader-1 (SGK3-PROTAC1) (HY-125878). PROTAC SGK3 degrader-2 exhibits inhibitory activity against SGK3, SGK1 and S6K1, with IC50 values of 0.6 μM, 1.4 μM and 1.7 μM, respectively, but fails to degrade SGK3. PROTAC SGK3 degrader-2 can serve as a control compound to investigate the specific effects of SGK3 degradation mediated by SGK3-PROTAC1 .
Cat. No.: HY-176824
CAS No.: 2376722-89-1
Research Areas:
308-R-C4-PEG3-C1-Boc is a SGK3 ligand-linker conjugate that can be used for synthesis of PROTAC SGK3 degrader-2(HY-176823) .
Cat. No.: HY-151009
CAS No.: 2376724-98-8
Research Areas:
308-R is a SGK3/SGK1/S6K1 inhibitor. 308-R exhibits an IC50 of 5 nM against human SGK3, an IC50 of 10 nM against human SGK1, and an IC50 of 1 nM against human S6K1. 308-R can be used in breast cancer research. It is also applicable to studies related to PROTAC synthesis, such as serving as the target protein ligand for PROTAC SGK3 degrader-2 (HY-176823) .
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