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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
PROTAC SMARCA2 degrader-22
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "PROTAC SMARCA2 degrader-22" in MCE Product Catalog:
Cat. No.: HY-169273
CAS No.: 2760246-90-8
Target:
Research Areas:
PROTAC SMARCA2 degrader-22 (Compound 5) is a PROTAC degrader for SMARCA2 with a degradation efficacy of 94% at 100 nM. PROTAC SMARCA2 degrader-22 inhibits the proliferation of cell A549 with an EC50 < 250 nM .
Cat. No.: HY-163875
CAS No.: 2568277-48-3
SMARCA2 degrader-14 (compound I-408) is a PROTAC degrader targeting SMARCA2 and SMARCA4; it degrades SMARCA2/4 proteins in A549 cells with the DC50s <100 nM, and the maximum degradation rate (Dmax%) >90 after 24 h of treatment .
Cat. No.: HY-163951
CAS No.: 2361116-63-2
Target:
Research Areas:
(S,R,S)-AHPC-Ac is a ligand for E3 ubiquitinase. (S,R,S)-AHPC-Ac can be used to synthesize PROTAC SMARCA2/4-degrader-22 (HY-163875) .
Cat. No.: HY-163952
Research Areas:
(S,R,S)-AHPC-Ac-CO-cyclohexene-Bpin is an E3 Ligase Ligand-Linker Conjugate. (S,R,S)-AHPC-Ac-CO-cyclohexene-Bpin can be used to synthesize PROTAC SMARCA2/4-degrader-22 (HY-163875) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
