38 Results for "

Prebiotics

" in MedChemExpress (MCE) Product Catalog:
Products (38)

38 Results for "Prebiotics" in MCE Product Catalog:

4
Inulin
Inulin
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4 Cited Publications
Cat. No.: HY-N7075
CAS No.: 9005-80-5
Category:  

Human Gut Microbiota Metabolites Polysaccharides Metabolic Disease Plants Compositae Endogenous metabolite Disease Research Fields Sophora tomentosa L. Saccharides

Target:  

Endogenous Metabolite

Inulin is an orally active prebiotic targeting the intestinal microbiota, selectively promoting the proliferation and activity of beneficial bacteria such as bifidobacteria and lactic acid bacteria, and playing a role in regulating the intestinal microecology. The functions of Inulin include: Fermentation by probiotics in the colon to produce short-chain fatty acids (such as butyrate and propionate), lowering the intestinal pH and inhibiting the overgrowth of harmful bacteria; Enhancing the intestinal barrier function and reducing endotoxin translocation; Directly scavenging free radicals (such as superoxide free radicals, hydroxyl free radicals) and activating antioxidant enzymes (SOD, CAT) to reduce oxidative stress. Inulin can also be used in the study of intestinal diseases (constipation, IBD), metabolic syndrome (diabetes, obesity) and liver damage by regulating glucose and lipid metabolism (such as reducing triglycerides, improving insulin sensitivity) and immune response (enhancing NK cell activity, inhibiting inflammatory factors)[1][2][3][4].
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Sintilimab
Sintilimab
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3 Cited Publications
Cat. No.: HY-P99048
CAS No.: 2072873-06-2
Synonyms: IBI308

Target:  

PD-1/PD-L1

Research Areas:  

Inflammation/Immunology Cancer

Sintilimab (IBI308) is a safe and effectivel humanized IgG4 monoclonal antibody that binds to PD-1 with a KD value of 74 pM. Sintilimab blocks the interaction of PD-1 with its ligands (PD-L1 and PL-L2), consequently helping to restore the endogenous antitumour T-cell response. Sintilimab combined with prebiotics inhibits tumor volume and regulates immune cell subpopulation balance in lung adenocarcinoma mice. Sintilimab can be used for the research of classical Hodgkin's lymphoma, non-small cell lung cancer and oesophageal cancer .
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Nystose
Nystose
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1 Cited Publications
Cat. No.: HY-N1499
CAS No.: 13133-07-8
Category:  

Polysaccharides Rubiaceae Metabolic Disease Plants Morinda officinalis How Disease Research Fields Saccharides

Target:  

Wnt β-catenin TGF-beta/Smad Bacterial

Nystose is a tetrasaccharide with two fructose molecules linked via beta (1→2) bonds to the fructosyl moiety of sucrose. Nystose exhibits prebiotic, immunomodulatory, and metabolism regulating activities. Nystose promotes the bone mineralization by activating the Wnt/β-catenin signaling pathway .
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3'-Sialyllactose sodium
3'-Sialyllactose sodium
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1 Cited Publications
Cat. No.: HY-108065A
CAS No.: 128596-80-5
Purity:  ≥98.0%
Synonyms: 3'-SL sodium
Category:  

Polysaccharides Animals Disease Research Fields Inflammation/Immunology Saccharides

Target:  

NF-κB

3'-Sialyllactose (3'-SL) sodium is a prebiotic, maintains immune homeostasis and exerts anti-inflammatory and anti-arthritic effects. 3'-Sialyllactose sodium is an ordinary carbohydrate with the lowest toxicity rating, it can be used for the research of inflammation .
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Lacto-N-tetraose
Lacto-N-tetraose
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1 Cited Publications
Cat. No.: HY-N9448
CAS No.: 14116-68-8
Category:  

Infection Human Gut Microbiota Metabolites Polysaccharides Endogenous metabolite Disease Research Fields Inflammation/Immunology Saccharides

Target:  

Bacterial

Lacto-N-tetraose is the significant core structure of human milk oligosaccharides (HMOs) naturally existing in human milk. Lacto-N-tetraose is consist of galactose, N-acetylglucosamine, and glucose moieties. Lacto-N-tetraose has prebiotic effect, immune regulatory effect, anti-inflammatory effects, intestinal cell responses regulatory effect, antibacterial activity and antiviral activity. Lacto-N-tetraose has been widely added to infant formula .
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3-Fucosyllactose
3-Fucosyllactose
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1 Cited Publications
Cat. No.: HY-N10528
CAS No.: 41312-47-4
Synonyms: 3-Fucosyl-D-lactose
Category:  

Infection Polysaccharides Animals Disease Research Fields Inflammation/Immunology Saccharides

Target:  

Bacterial Enterovirus

3-Fucosyllactose (3-Fucosyl-D-lactose) is one of the major fucosylated oligosaccharides found in human breast milk. 3-Fucosyllactose shows prebiotic, immunomodulator, neonatal brain development, and antimicrobial function .
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Stachyose tetrahydrate
Stachyose tetrahydrate
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1 Cited Publications
Cat. No.: HY-113529
CAS No.: 10094-58-3
Purity:  ≥98.0%
Category:  

other families Polysaccharides Plants Disease Research Fields Saccharides Cancer

Target:  

Apoptosis Endogenous Metabolite

Stachyose tetrahydrate, a functional oligosaccharide, acts as a prebiotic. Stachyose tetrahydrate can prevent indirectly colon cancer cell growth by promoting the proliferation of probiotics or producing beneficial materials in the intestine .
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Isomaltotetraose
Isomaltotetraose
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1 Cited Publications
Cat. No.: HY-N7948
CAS No.: 35997-20-7
Category:  

Polysaccharides Microorganisms Other Diseases Disease Research Fields Saccharides

Target:  

Endogenous Metabolite

Isomaltotetraose is an orally active branched isomaltooligosaccharide with α-(1,6) glycosidic linkages. Isomaltotetraose is a prebiotic oligosaccharide present in honey and also a component of isomaltooligosaccharide mixtures. Isomaltotetraose maintains the growth of Prevotella or sustains the *Prevotella* enterotype in both in vitro systems and mouse models .
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Stachyose hydrate
Stachyose hydrate
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1 Cited Publications
Cat. No.: HY-N0299
CAS No.: 54261-98-2
Category:  

Polysaccharides Scrophulariaceae Plants Rehmannia glutinosa (Gaert.) Libosch. ex Fisch. et Mey Disease Research Fields Inflammation/Immunology Saccharides

Target:  

Endogenous Metabolite Apoptosis

Stachyose hydrate is an orally active prebiotic that enhances the growth and activity of beneficial bacteria. Stachyose hydrate has hypoglycemic effects and can improve inflammation by regulating gut microbiota. In addition, Stachyose hydrate can induce plant cell apoptosis (Apoptosis). Stachyose hydrate can be used in research on inflammation, gastrointestinal diseases, and agriculture .
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Kojibiose
Kojibiose
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1 Cited Publications
Cat. No.: HY-113133
CAS No.: 2140-29-6
Purity:  99.76%
Category:  

Microorganisms

Target:  

Glycosidase

Kojibiose, an orally active prebiotic disaccharide, can specifically inhibit the activity of α-glucosidase I. kojibiose is a proliferation factor for Bifidobacterium, lactic acid bacteria, and eubacteria. kojibiose is a low-calorie sweetener capable of increasing the absorption of iron. Kojibiose exhibits antitoxic activity. Kojibiose reduces hepatic expression of inflammatory markers in vivo .
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N-Acetyllactosamine
N-Acetyllactosamine
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Cat. No.: HY-126854
CAS No.: 32181-59-2
Purity:  99.95%
Synonyms: N-Acetyl-D-lactosamine
Category:  

Natural Products Microorganisms

Target:  

Endogenous Metabolite Galectin

N-Acetyllactosamine (N-Acetyl-D-lactosamine), a nitrogen-containing disaccharide, is a galectin-3 inhibitor, which is an important component of various oligosaccharides such as glycoproteins and sialyl Lewis X. N-Acetyllactosamine can be used as the starting material for the synthesis of various oligosaccharides. N-Acetyllactosamine has prebiotic effects .
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Isomaltose
Isomaltose
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Cat. No.: HY-N3018
CAS No.: 499-40-1
Synonyms: 6-O-α-D-Glucopyranosyl-D-glucose; D-Isomaltose
Category:  

Human Gut Microbiota Metabolites Polysaccharides Metabolic Disease Endogenous metabolite Disease Research Fields Saccharides

Target:  

Endogenous Metabolite Parasite

Isomaltose (6-O-α-D-Glucopyranosyl-D-glucose) is a glucose disaccharide. Isomaltose induces G-CSF secretion via heat-induced oxidative polymerization of glucose groups into high-molecular-weight compounds. Isomaltose modulates cecal bacterial cluster structure in mice. Isomaltose exhibits low glycemic index, slow hydrolysis, and prebiotic properties. Isomaltose reduces in vivo Cryptosporidium parvum colonization in neonatal mice. Isomaltose can be used for the research of Cryptosporidium parvum infection .
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Maltitol
Maltitol
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Cat. No.: HY-B2122
CAS No.: 585-88-6
Category:  

Lotus filicaulis Leguminosae Plants Saccharides Monosaccharides

Target:  

PPAR Fatty Acid Synthase (FASN)

Maltitol is an orally active polyol and sugar alcohol sweetener produced by the hydrogenation of maltose. Maltitol can replace sucrose and has characteristics of having a minor impact on blood sugar and potential prebiotic effects .
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D-Tagatose
D-Tagatose
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Cat. No.: HY-42680
CAS No.: 87-81-0
Synonyms: D-(-)-Tagatose
Category:  

Metabolic Disease Endogenous metabolite Disease Research Fields Sweeteners Saccharides Food Research Monosaccharides

Target:  

Endogenous Metabolite

D-Tagatose (D-(-)-Tagatose) is a natural low-calorie rare sugar. D-Tagatose inhibits the activities of sucrase, maltase and intestinal disaccharidases, reduces the digestion of sucrose and starch, and blocks the absorption of sucrose, maltose and glucose. D-Tagatose promotes glucokinase activity and inhibits glycogen phosphorylase activity via tagatose-1-phosphate, regulates the synthesis and decomposition of hepatic glycogen, reduces postprandial and fasting blood glucose levels, and improves hyperinsulinemia. D-Tagatose regulates lipid profiles, stimulates GLP-1 secretion, and exhibits prebiotic effects. D-Tagatose is a bulking sweetener. D-Tagatose can be used in research related to diabetes, hyperlipidemia, dental caries, atherosclerosis and type 2 diabetes .
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Fructooligosaccharides
Fructooligosaccharides
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Cat. No.: HY-107863
CAS No.: 308066-66-2
Purity:  99.45%
Synonyms: Oligolevulose
Fructooligosaccharides (Oligolevulose) are a class of orally active dietary fibers and prebiotics. Fructooligosaccharides exist in foods such as breast milk, wheat, honey, onions, garlic and bananas. Fructooligosaccharides resist hydrolysis by the body's digestive enzymes and stimulate the growth of beneficial intestinal bacteria through colonic fermentation. Fructooligosaccharides significantly prevent bone loss in the femur and lumbar spine .
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3'-Sialyllactose
3'-Sialyllactose
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Cat. No.: HY-108065
CAS No.: 35890-38-1
Synonyms: 3'-SL
Category:  

Natural Products Animals Disease Research Fields Inflammation/Immunology

Target:  

NF-κB

3'-Sialyllactose (3'-SL) is a prebiotic, maintains immune homeostasis and exerts anti-inflammatory and anti-arthritic effects. 3'-Sialyllactose is an ordinary carbohydrate with the lowest toxicity rating, it can be used for the research of inflammation .
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Dextran T0.8 (MW 800)
Dextran T0.8 (MW 800)
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Cat. No.: HY-112624E
CAS No.: 9004-54-0
Synonyms: Dextran 0.8; Dextran D0.8; Dextran T0.8(MW 640-960)
Dextran T0.8 (Dextran 0.8; Dextran T0.8(MW 640-960)) is a food additive with a porous network structure that exhibits strong hydration capacity and low browning activity. Dextran T0.8 (MW 800) can improve the coagulation of dairy products and is used as a prebiotic in baked goods. Dextran T0.8 (MW 800) is non-toxic to HeLa cells at a concentration of ~500 μg/mL and has a low relative browning rate in the Maillard reaction. The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong the half-life of drugs, increase local concentrations, and reduce the activity of immune clearance .
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Polydextrose
Polydextrose
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Cat. No.: HY-W134326
CAS No.: 68424-04-4
Polydextrose is an orally active prebiotic. Polydextrose promotes the growth of Pediococcus pentosaceus ATCC 43200. Polydextrose reduces cholesterol and synergistically lowers blood sugar with Sitagliptin (HY-13749). Currently, it is mainly used in the research of diseases such as hyperlipidemia, type 2 diabetes, and postoperative iron deficiency anemia .
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Beef extract
Beef extract
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Cat. No.: HY-156261
CAS No.: 68990-09-0
Beef extract is a common ingredient in the preparation of biological culture media .
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α-Cytidine
α-Cytidine
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Cat. No.: HY-W576440
CAS No.: 13913-16-1
Target:  

Nucleoside Antimetabolite/Analog

Research Areas:  

Others

α-Cytidine is a nucleoside. Under appropriate prebiotic conditions, α-Cytidine can be generated from ribose 5'-phosphate, cyanamide and cyanoacetylene .
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