31 Results for "

Rheumatic diseases

" in MedChemExpress (MCE) Product Catalog:
Products (31)

31 Results for "Rheumatic diseases" in MCE Product Catalog:

10
10 Publications Verification
Cat. No.: HY-N0847
CAS No.: 68370-47-8
Micheliolide is a sesquiterpene lactone with anti-cancer and anti-inflammatory effects, which is derived from Michelia compressa and Michelia champaca. Micheliolide can attenuate high glucose-stimulated NF-κB activation, IκBα degradation, and the expression of MCP-1, TGF-β1, and FN in mouse mesangial cells. Micheliolide inhibits LPS (HY-D1056)-induced activation of NF-κB and PI3K/Akt/p70S6K pathways to play an anti-inflammatory role. Micheliolide inhibits dextran sodium sulphate (DSS) (HY-116282)-induced inflammatory intestinal disease, colitis-associated cancer and rheumatic arthritis .
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8
8 Cited Publications
Cat. No.: HY-B0256
CAS No.: 446-86-6
Synonyms: BW 57-322
Target:  

Apoptosis

Research Areas:  

Inflammation/Immunology Cancer

Azathioprine (BW 57-322) is an orally active immunosuppressive agent. Azathioprine can be converted in vivo to the active metabolite 6-mercaptopurine (6-MP). Azathioprine has myelosuppressive effects and induces apoptosis .
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1
1 Cited Publications
Cat. No.: HY-106579
CAS No.: 33005-95-7
Purity:  98.74%
Target:  

COX

Research Areas:  

Inflammation/Immunology

Tiaprofenic acid is an orally active nonsteroidal anti-inflammatory agent (NSAID) with anti-inflammatory and analgesic potency. Tiaprofenic acid inhibits prostaglandin synthesis by suppressing cyclo-oxygenase (COX). Tiaprofenic acid can be used in the treatment of rheumatic diseases .
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1
1 Cited Publications
Cat. No.: HY-W014750
CAS No.: 779-30-6
3-Acetamidocoumarin plays an important role in biology and medicine. 3-Acetamidocoumarin has physiological effects and has been used for many diseases such as research of burns, brucellosis-rheumatic diseases and cancer .
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Cat. No.: HY-W040672
CAS No.: 1553-60-2
Synonyms: Dytransin
Target:  

COX

Research Areas:  

Inflammation/Immunology

Ibufenac (Dytransin) is an orally active nonsteroidal anti-inflammatory agent. Ibufenac exerts anti-inflammatory, analgesic and antipyretic effects. Ibufenac is being studied for the treatment of rheumatic diseases such as rheumatoid arthritis .
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Cat. No.: HY-17361
CAS No.: 30544-47-9
Target:  

COX

Research Areas:  

Inflammation/Immunology

Etofenamate, a non-steroid anti-inflammatory agent (NSAID) and a non-selective COX inhibitor, possesses analgesic, anti-rheumatic, antipyretic and anti-inflammatory properties. Etofenamate is used in the research for osteoarthritis, arthritis and other inflammatory diseases .
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Cat. No.: HY-106583
CAS No.: 87234-24-0
Purity:  99.19%
Synonyms: Cinnoxicam; SPA-S-510; Sinartol
Target:  

COX

Research Areas:  

Inflammation/Immunology

Piroxicam cinnamate (Cinnoxicam) is a cyclooxygenase (COX) inhibitor, with anti-inflammatory activity. Piroxicam cinnamate is stable under gastric conditions, can be used for inflammatory-degenerative osteoarticular diseases, rheumatic disorders, and varicocele (VC) associated oligoasthenospermia research .
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Cat. No.: HY-N0131R
CAS No.: 83-48-7
Synonyms: Stigmasterin (Standard)
Stigmasterol (Standard) is the analytical standard of Stigmasterol (HY-N0131). This product is intended for research and analytical applications. Stigmasterol is a plant sterol which has been focused on the cholesterol-lowering activity and is valued as an anti-stiffness factor in the therapy of rheumatic diseases.
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Cat. No.: HY-W338346
CAS No.: 2016-36-6
Salicylate choline is an orally active derivative of Aspirin (acetylsalicylic acid) (HY-14654). Salicylate choline significantly reduces IL-1β, IL-6, TNF-α and IL-10 levels in cells. Salicylate choline enhances the anti-tumor activity of the CRM1 inhibitor Selinexor (KPT-330) (HY-17536) through inducing S-phase cell cycle arrest and impairing DNA damage repair. Salicylate choline combined with Selinexor demonstrates excellent anti-tumor efficacy in mice xenograft model harboring JeKo-1 cells. Salicylate choline can be used for the study of rheumatic diseases, inflammation and cancer .
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Cat. No.: HY-B0256R
CAS No.: 446-86-6
Synonyms: BW 57-322 (Standard)
Azathioprine (Standard) is the analytical standard of Azathioprine. This product is intended for research and analytical applications. Azathioprine (BW 57-322) is an orally active immunosuppressive agent. Azathioprine can be converted in vivo to the active metabolite 6-mercaptopurine (6-MP). Azathioprine has myelosuppressive effects and induces apoptosis .
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Cat. No.: HY-B1130
CAS No.: 34552-84-6
Target:  

COX

Research Areas:  

Inflammation/Immunology

Isoxicam is an orally active nonsteroidal anti-inflammatory compound and a COX-1/COX-2 inhibitor. Isoxicam exhibits potent anti-inflammatory activity in rat models of inflammation and significantly lower ulcerogenic risk. Isoxicam can be used for the study of inflammatory diseases and rheumatic disorders .
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Cat. No.: HY-B1130R
CAS No.: 34552-84-6
Target:  

Reference Standards COX

Research Areas:  

Inflammation/Immunology

Isoxicam (Standard) is the analytical standard of Isoxicam (HY-B1130). This product is intended for research and analytical applications. Isoxicam is an orally active nonsteroidal anti-inflammatory compound and a COX-1/COX-2 inhibitor. Isoxicam exhibits potent anti-inflammatory activity in rat models of inflammation and significantly lower ulcerogenic risk. Isoxicam can be used for the study of inflammatory diseases and rheumatic disorders .
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Cat. No.: HY-145455
CAS No.: 22933-72-8
Purity:  97.03%
Target:  

Bacterial

Research Areas:  

Infection

Salazopyridazine is an antibacterial agent. Salazopyridazine shows activities against ulcerative colitis. Salazopyridazine can be used for the research of rheumatic diseases .
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Cat. No.: HY-127150
CAS No.: 17449-96-6
Synonyms: Perclusone
Target:  

Collagen

Research Areas:  

Inflammation/Immunology

Clofezone (Perclusone) is an antirheumatic agent that inhibits collagen formation in rat Chondrus granulomas. Clofezone can be used in the study of various rheumatic diseases, especially arthritis (RA) and ankylosing spondylitis (AS) .
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Cat. No.: HY-106579S
CAS No.: 2740831-64-3
Purity:  96.32%
Tiaprofenic acid-d3 is a deuterium labeled Tiaprofenic acid. Tiaprofenic acid is a nonsteroidal anti-inflammatory agent (NSAID) mainly used in the treatment of rheumatic diseases .
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Cat. No.: HY-E70233
CAS No.: 9068-78-4
Target:  

Others

Research Areas:  

Inflammation/Immunology

Histidyl-tRNA synthetase, human is responsible for the synthesis of histidyl-transfer RNA, which is essential for the incorporation of histidine into proteins. Histidyl-tRNA synthetase has been found to act as a particularly important antigen in autoimmune diseases such as rheumatic arthritis or myositis .
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Cat. No.: HY-105630
CAS No.: 27315-91-9
Synonyms: LD-4644
Target:  

Others

Research Areas:  

Inflammation/Immunology

Pipebuzone (LD 4644) is an anti-inflammatory, antipyretic and analgesic agent. Pipebuzone plays an important raol in rheumatic diseases .
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Cat. No.: HY-N0847R
CAS No.: 68370-47-8
Micheliolide is a sesquiterpene lactone with anti-cancer and anti-inflammatory effects, which is derived from Michelia compressa and Michelia champaca. Micheliolide can attenuate high glucose-stimulated NF-κB activation, IκBα degradation, and the expression of MCP-1, TGF-β1, and FN in mouse mesangial cells. Micheliolide inhibits LPS (HY-D1056)-induced activation of NF-κB and PI3K/Akt/p70S6K pathways to play an anti-inflammatory role. Micheliolide inhibits dextran sodium sulphate (DSS) (HY-116282)-induced inflammatory intestinal disease, colitis-associated cancer and rheumatic arthritis .
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Cat. No.: HY-W040672R
CAS No.: 1553-60-2
Synonyms: Dytransin (Standard)
Target:  

Reference Standards COX

Research Areas:  

Inflammation/Immunology

Ibufenac (Dytransin) is an orally active nonsteroidal anti-inflammatory agent. Ibufenac exerts anti-inflammatory, analgesic and antipyretic effects. Ibufenac is being studied for the treatment of rheumatic diseases such as rheumatoid arthritis .
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Cat. No.: HY-N0131S1
CAS No.: 2260669-29-0
Synonyms: Stigmasterin-d5-1
Stigmasterol-d5-1 is deuterium labeled Stigmasterol. Stigmasterol is a plant sterol which has been focused on the cholesterol-lowering activity and is valued as an anti-stiffness factor in the therapy of rheumatic diseases .
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