1. Immunology/Inflammation
  2. COX
  3. Tiaprofenic acid

Tiaprofenic acid 

Cat. No.: HY-106579 Purity: >98.0%
Handling Instructions

Tiaprofenic acid is an orally active nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory and analgesic potency. Tiaprofenic acid inhibits prostaglandin synthesis by suppressing cyclo-oxygenase (COX). Tiaprofenic acid can be used in the treatment of rheumatic diseases.

For research use only. We do not sell to patients.

Tiaprofenic acid Chemical Structure

Tiaprofenic acid Chemical Structure

CAS No. : 33005-95-7

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10 mM * 1  mL in DMSO USD 72 In-stock
Estimated Time of Arrival: December 31
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10 mg USD 95 Get quote
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Based on 1 publication(s) in Google Scholar

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Description

Tiaprofenic acid is an orally active nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory and analgesic potency. Tiaprofenic acid inhibits prostaglandin synthesis by suppressing cyclo-oxygenase (COX). Tiaprofenic acid can be used in the treatment of rheumatic diseases[1].

In Vivo

Female Lewis rats received either Tiaprofenic acid (as an intravenous (iv.) bolus injection of 15 mg/kg and constant infusion of 0.02 mg/min) for 6 h. Tiaprofenic acid results in a significant decrease in serum sulfate concentrations and increase in sulfate clearance ratio. There is also a significant decrease in the fraction of sulfate reabsorbed by the kidneys[2].

Molecular Weight

260.31

Formula

C₁₄H₁₂O₃S

CAS No.

33005-95-7

SMILES

O=C(C1=CC=CC=C1)C2=CC=C(C(C)C(O)=O)S2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
References
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Keywords:

Tiaprofenic acidCOXCyclooxygenasenonsteroidalanti-inflammatorydruganalgesicrheumatoidarthritisosteoarthritisInhibitorinhibitorinhibit

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Tiaprofenic acid
Cat. No.:
HY-106579
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