17449-96-6
Chemical Structure
Clofezone
Synonym(s): Perclusone
- CAS No.: 17449-96-6
- Formula:C33H41ClN4O4
- Molecular Weight:593.16
IUPAC Name: 2-(4-chlorophenoxy)-N-(2-(diethylamino)ethyl)acetamide compound with 4-butyl-1,2-diphenylpyrazolidine-3,5-dione (1:1)
InChIKey: ICBCZMIEENEERJ-UHFFFAOYSA-N
SMILES: O=C(COC1=CC=C(C=C1)Cl)NCCN(CC)CC.O=C(N(N(C2=O)C3=CC=CC=C3)C4=CC=CC=C4)C2CCCC
Biological Activity: Clofezone (Perclusone) is an antirheumatic agent that inhibits collagen formation in rat Chondrus granulomas. Clofezone can be used in the study of various rheumatic diseases, especially arthritis (RA) and ankylosing spondylitis (AS)[1][2].
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Clofezone | Clofezone (Perclusone) is an antirheumatic agent that inhibits collagen formation in rat Chondrus granulomas. Clofezone can be used in the study of various rheumatic diseases, especially arthritis (RA) and ankylosing spondylitis (AS). | |||||||||||||||||||||
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- [1]. Brettschneider I, et al. Effect of some antirheumatics on connective tissue components. Arzneimittelforschung. 1976;26(5):846-8. [Content Brief]
- [2]. Celik CM. Erfahrungen in der Behandlung rheumatoider Erkrankungen mit unterschiedlichen Clofezon-Dosen [Experiences in the management of rheumatoid diseases using different clofezone doses]. Z Rheumatol. 1976 May-Jun;35(5-6):240-7. [Content Brief]
Keywords
