Rhodamine 6G

By Targets:	Apoptosis (1) Caspase (1) Drug Derivative (1) Environmental Pollutants (1) Fluorescent Dye (11) P-glycoprotein (1) Reactive Oxygen Species (ROS) (1) Reference Standards (1) Ser/Thr Protease (1)
By Research Areas:	Cancer (5) Metabolic Disease (1)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-D0309

Rhodamine 6G 4 Publications Verification Basic Red 1	Environmental Pollutants Fluorescent Dye	Cancer
Rhodamine dyes are membrane-permeable cationic fluorescent probes that specifically recognize mitochondrial membrane potentials, thereby attaching to mitochondria and producing bright fluorescence, and at certain concentrations, rhodamine dyes have low toxicity to cells, so they are commonly used to detect mitochondria in animal cells, plant cells, and microorganisms .

HY-D1599

Rhodamine 6G hydrazide R6GH	Fluorescent Dye	Others
Rhodamine 6G hydrazide (R6GH) is a fluorescent dye. Rhodamine 6G hydrazide can be used in selective colorimetric and fluorescent sensing .

HY-D0309R

Rhodamine 6G (Standard) Basic Red 1 (Standard)	Fluorescent Dye Reference Standards	Cancer
Rhodamine 6G (Standard) is the analytical standard of Rhodamine 6G. This product is intended for research and analytical applications. Rhodamine dyes are membrane-permeable cationic fluorescent probes that specifically recognize mitochondrial membrane potentials, thereby attaching to mitochondria and producing bright fluorescence, and at certain concentrations, rhodamine dyes have low toxicity to cells, so they are commonly used to detect mitochondria in animal cells, plant cells, and microorganisms .

HY-W247098

Dihydrorhodamine 6G DHR 6G	Reactive Oxygen Species (ROS)	Cancer
Dihydrorhodamine 6G (DHR 6G) is the reduced form of Rhodamine 6G, which is used as fluorescent mitochondrial dye. It is nonfluorescent, but it readily enters most of the cells and is oxidized by oxidative species or by cellular redox systems to the fluorescent rhodamine 6G that accumulates in mitochondrial membranes. Dihydrorhodamine 6G is useful for detecting reactive oxygen species (ROS) including superoxide .

HY-W127780

Rhodamine 6G perchlorate Basic Red 1 perchlorate	Fluorescent Dye	Others
Rhodamine dyes are membrane-permeable cationic fluorescent probes that specifically recognize mitochondrial membrane potentials, thereby attaching to mitochondria and producing bright fluorescence, and at certain concentrations, rhodamine dyes have low toxicity to cells, so they are commonly used to detect mitochondria in animal cells, plant cells, and microorganisms .

HY-D3056

*5(6)-Rhodamine* 6G maleimide**	Fluorescent Dye	Others
5(6)-Rhodamine 6G maleimide is a maleimide-based fluorescent reagent based on Rhodamine 6G (HY-D0309). Maleimide can be labeled by forming a stable thioester structure through an affinity addition reaction with a thiol group (-SH) (Ex/Em = 526/547 nm).

HY-D3053

*5(6)-Rhodamine* 6G NHS ester**	Fluorescent Dye	Others
5(6)-Rhodamine 6G NHS ester is a reactive ester fluorescent reagent based on Rhodamine 6G (HY-D0309). NHS ester is a highly reactive ester capable of covalently coupling with primary amine groups in molecules such as proteins, peptides, amino sugars, and nucleic acids to form stable amide bonds (Ex/Em = 526/547 nm).

HY-D3054

5(6)-Rhodamine 6G amine	Fluorescent Dye	Others
5(6)-Rhodamine 6G amine is a primary amine fluorescent reagent based on Rhodamine 6G (HY-D0309). Primary amines can be covalently linked with various functional groups such as carboxylic acids, active esters (e.g., NHS esters), and isothiocyanates to achieve labeling (Ex/Em = 526/547 nm).

HY-172268

R6G phosphoramidite, 6-isomer	Fluorescent Dye	Others
R6G phosphoramidite for oligonucleotide synthesis, pure 6-isomer. R6G (rhodamine 6G) is a xanthene dye of the rhodamine family with high fluorescence quantum yield and high molar extinction coefficient. Relative to those of fluorescein, the absorption (518 nm) and emission (542 nm) maxima of 6-R6G are shifted into the long-wave region.

HY-157483

P-gp inhibitor 18	P-glycoprotein	Cancer
P-gp inhibitor 18 (compound 6G) is a potent inhibitor of P-gp. P-gp inhibitor 18 inhibits rhodamine 123 efflux in the P-gp overexpressed leukemia cells, K562/Dox .

HY-N7539

Cognac oil	Others	Metabolic Disease
Cognac oil, mainly found in wine lees, has unique fatty acid profiles, including Palmitic acid (59.26%), Linoleic acid (11.92%), Myristic acid (8.97%), Oleic acid (8.3%) and other fatty acids. Cognac oil leads to a general increase in the permeation of R6G (Rhodamine 6G) across all the membranes .

HY-P4403

Z-DEVD-R110 (Z-Asp-Glu-Val-Asp)₂-Rhodamine 110	Fluorescent Dye Apoptosis Caspase	Others
Z-DEVD-R110 ((Z-Asp-Glu-Val-Asp)₂-Rhodamine 110) is a fluorogenic caspase-3/7 substrate. Z-DEVD-R110 can be used to detect apoptosis. Z-DEVD-R110 is a rhodamine derivative with two four–amino acid (DEVD) peptides linked to the fuorophore .

HY-P10322

Z-IETD-R110	Fluorescent Dye	Cancer
Z-IETD-R110 is a fluorescent substrate of caspases. Z-IETD-R110 acts as a substrate for caspase-8. When caspase-8 is activated, it can recognize and cut Z-IETD-R110, releasing fluorophore, which can be detected by fluorescence microscopy. Z-IETD-R110 can be used to study oxidative stress-induced apoptosis, particularly in pancreatic acinar cells .

HY-P11476

(Z-AR)2Rh110	Ser/Thr Protease Fluorescent Dye Drug Derivative	Others
(Z-AR)2Rh110 is a Rhodamine derivative. (Z-AR)2Rh110 can be hydrolyzed by trypsin .

Cat. No.	Product Name	Type

HY-D0309

Rhodamine 6G 4 Publications Verification Basic Red 1	Fluorescent Dyes
Rhodamine dyes are membrane-permeable cationic fluorescent probes that specifically recognize mitochondrial membrane potentials, thereby attaching to mitochondria and producing bright fluorescence, and at certain concentrations, rhodamine dyes have low toxicity to cells, so they are commonly used to detect mitochondria in animal cells, plant cells, and microorganisms .

HY-D1599

Rhodamine 6G hydrazide R6GH	Fluorescent Dyes
Rhodamine 6G hydrazide (R6GH) is a fluorescent dye. Rhodamine 6G hydrazide can be used in selective colorimetric and fluorescent sensing .

HY-D0309R

Rhodamine 6G (Standard) Basic Red 1 (Standard)	Fluorescent Dyes
Rhodamine 6G (Standard) is the analytical standard of Rhodamine 6G. This product is intended for research and analytical applications. Rhodamine dyes are membrane-permeable cationic fluorescent probes that specifically recognize mitochondrial membrane potentials, thereby attaching to mitochondria and producing bright fluorescence, and at certain concentrations, rhodamine dyes have low toxicity to cells, so they are commonly used to detect mitochondria in animal cells, plant cells, and microorganisms .

Rhodamine 6G (Standard)

Basic Red 1 (Standard)

Fluorescent Dyes

Rhodamine 6G (Standard) is the analytical standard of Rhodamine 6G. This product is intended for research and analytical applications. Rhodamine dyes are membrane-permeable cationic fluorescent probes that specifically recognize mitochondrial membrane potentials, thereby attaching to mitochondria and producing bright fluorescence, and at certain concentrations, rhodamine dyes have low toxicity to cells, so they are commonly used to detect mitochondria in animal cells, plant cells, and microorganisms .

HY-D3056

*5(6)-Rhodamine* 6G maleimide**	Fluorescent Dyes
5(6)-Rhodamine 6G maleimide is a maleimide-based fluorescent reagent based on Rhodamine 6G (HY-D0309). Maleimide can be labeled by forming a stable thioester structure through an affinity addition reaction with a thiol group (-SH) (Ex/Em = 526/547 nm).

HY-D3053

*5(6)-Rhodamine* 6G NHS ester**	Fluorescent Dyes
5(6)-Rhodamine 6G NHS ester is a reactive ester fluorescent reagent based on Rhodamine 6G (HY-D0309). NHS ester is a highly reactive ester capable of covalently coupling with primary amine groups in molecules such as proteins, peptides, amino sugars, and nucleic acids to form stable amide bonds (Ex/Em = 526/547 nm).

HY-D3054

5(6)-Rhodamine 6G amine	Fluorescent Dyes
5(6)-Rhodamine 6G amine is a primary amine fluorescent reagent based on Rhodamine 6G (HY-D0309). Primary amines can be covalently linked with various functional groups such as carboxylic acids, active esters (e.g., NHS esters), and isothiocyanates to achieve labeling (Ex/Em = 526/547 nm).

HY-172268

R6G phosphoramidite, 6-isomer	Fluorescent Dyes
R6G phosphoramidite for oligonucleotide synthesis, pure 6-isomer. R6G (rhodamine 6G) is a xanthene dye of the rhodamine family with high fluorescence quantum yield and high molar extinction coefficient. Relative to those of fluorescein, the absorption (518 nm) and emission (542 nm) maxima of 6-R6G are shifted into the long-wave region.

Cat. No.	Product Name	Type

HY-W127780

Rhodamine 6G perchlorate Basic Red 1 perchlorate	Biochemical Assay Reagents
Rhodamine dyes are membrane-permeable cationic fluorescent probes that specifically recognize mitochondrial membrane potentials, thereby attaching to mitochondria and producing bright fluorescence, and at certain concentrations, rhodamine dyes have low toxicity to cells, so they are commonly used to detect mitochondria in animal cells, plant cells, and microorganisms .

Cat. No.	Product Name	Target	Research Area

HY-P4403

Z-DEVD-R110 (Z-Asp-Glu-Val-Asp)₂-Rhodamine 110	Fluorescent Dye Apoptosis Caspase	Others
Z-DEVD-R110 ((Z-Asp-Glu-Val-Asp)₂-Rhodamine 110) is a fluorogenic caspase-3/7 substrate. Z-DEVD-R110 can be used to detect apoptosis. Z-DEVD-R110 is a rhodamine derivative with two four–amino acid (DEVD) peptides linked to the fuorophore .

HY-P10322

Z-IETD-R110	Fluorescent Dye	Cancer
Z-IETD-R110 is a fluorescent substrate of caspases. Z-IETD-R110 acts as a substrate for caspase-8. When caspase-8 is activated, it can recognize and cut Z-IETD-R110, releasing fluorophore, which can be detected by fluorescence microscopy. Z-IETD-R110 can be used to study oxidative stress-induced apoptosis, particularly in pancreatic acinar cells .

HY-P11476

(Z-AR)2Rh110	Ser/Thr Protease Fluorescent Dye Drug Derivative	Others
(Z-AR)2Rh110 is a Rhodamine derivative. (Z-AR)2Rh110 can be hydrolyzed by trypsin .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N7539

Cognac oil	other families Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Plants Disease Research Fields Source Classification	Others
Cognac oil, mainly found in wine lees, has unique fatty acid profiles, including Palmitic acid (59.26%), Linoleic acid (11.92%), Myristic acid (8.97%), Oleic acid (8.3%) and other fatty acids. Cognac oil leads to a general increase in the permeation of R6G (Rhodamine 6G) across all the membranes .

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
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Rhodamine 6G

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