1 Result for "

Rosuvastatin lactone (Standard)

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "Rosuvastatin lactone (Standard)" in MCE Product Catalog:

Cat. No.: HY-138166R
CAS No.: 503610-43-3
Rosuvastatin lactone (Standard) is the analytical standard of Rosuvastatin lactone. This product is intended for research and analytical applications. Rosuvastatin lactone is a metabolite of Rosuvastatin (HY-17504A), a statin lipid-lowering agent and HMG-CoA inhibitor. Rosuvastatin lactone exhibits endothelium-independent and HMG-CoA reductase-independent vasorelaxant activity in rat aortic rings, and its vasorelaxant effect is jointly mediated by NO produced by inducible nitric oxide synthase (iNOS) located in vascular smooth muscle and activation of potassium channels. Rosuvastatin lactone itself has no lipid-lowering effect .
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