1 Result for "

Sandoz 58-035

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Sandoz 58-035" in MCE Product Catalog:

Cat. No.: HY-112487
CAS No.: 78934-83-5
Purity:  99.35%
Target:  

Acyltransferase

Research Areas:  

Metabolic Disease

Sandoz 58-035 is a selective acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor. Sandoz 58-035 inhibits this enzyme in intact cells and isolated microsomal fractions. Sandoz 58-035 blocks the esterification of exogenous vesicle-derived cholesterol and the incorporation of oleic acid into cellular cholesterol esters, reducing the formation and accumulation of cholesterol esters. Sandoz 58-035 causes a slight increase in cellular free cholesterol, and at high concentrations, it also causes a slight reduction in overall cellular protein synthesis. Sandoz 58-035 can be used in studies related to cellular cholesterol regulation .
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