1 Result for "

Sennidin B (Standard)

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Sennidin B (Standard)" in MCE Product Catalog:

Cat. No.: HY-N6935R
CAS No.: 517-44-2
Sennidin B Standard is the analytical standard of Sennidin B (HY-N6935). This product is intended for research and analytical applications. Sennidin B is an anthraquinone compound isolated from Cassia angustifolia. Sennidin B is a DPP-4 inhibitor with an IC50 of 39.39 μM. Sennidin B is an insect chitinase inhibitor with a Ki of 80 nM against OfChi-h. Sennidin B competitively inhibits chitinase activity by forming π-π stacking interactions with key tryptophan residues in the active site through a folded conformation. Sennidin B activates PI3K/Akt to promote glucose uptake in adipocytes. Sennidin B can be used for the development of biopesticides and research on type 2 diabetes and metabolism-related signaling pathways .
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